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Antibiotic Treatment of Asymptomatic Bacteriuria

Jon I. Scheinman, MD; Donnell J. Hester, PhD; Suzanne S. Integlia; Carla P. Harvey
Am J Dis Child. 1973;125(3):349-352. doi:10.1001/archpedi.1973.04160030027005.
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Asymptomatic bacteriuria was detected in 27 (1.14%) of 1,389 girls utilizing an automatic urine collection seat with results confirmed by two additional clean-voided urine collections or by suprapubic bladder aspiration. Neither a microculture technique nor overnight refrigeration of specimens was found satisfactory for this program. Except for a suggestion of increased frequency of micturition, neither the clinical data obtained from parents nor the presence of proteinuria or pyuria were helpful in identifying girls with bacteriuria.

In a controlled trial of therapy, six to 12 month follow-up of 20 patients revealed a significant advantage of a brief course of antibiotic administration in eliminating bacteriuria (P =.02).


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