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January 1973, Vol 125, No. 1 >
Article | January 1973

Cyclopia FREE

Gabriel Khudr, MD; Lars Olding, MD
[+] Author Affiliations

Received for publication Feb 11, 1972; accepted Sept 26.

Reprint requests to University of California, School of Medicine, P.O. Box 109, La Jolla, Calif 92037 (Dr. Khudr).


Am J Dis Child. 1973;125(1):120-122. doi:10.1001/archpedi.1973.04160010082020.
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References
Comments

Cyclopism is an unusual anomaly. The present case is the result of a complicated pregnancy. A study of the skull bones is presented and teratogenic effects of salicylates, cortisone, and viruses are discussed.

REFERENCES

1 +
Lilliard RL:  The cyclop deformity . Rocky Mt Med J 61:32-34, (Dec) 1964;.
2 +
Arakaki DI, Waxman SH:  Trisomy-D in cyclops . J Pediatr 74:620-625, 1969;.
3 +
Toews HA, Jones HW:  Cyclopia in association with D-trisomy and gonadal agenesis . Am J Obstet Gynecol 102:53-56, 1968;.
4 +
Halbrecht I, et al:  Trisomy-D in cyclops . Obstet Gynecol 37:391-393, 1971;.
5 +
Schval AR:  Recent progress in human chromosome analysis and its relation to the sex chromatin . Am J Med 31:397-441, 1961;.
6 +
Pfitzer P, Müntefering H:  Cyclopism as a hereditary malformation . Nature 217:1071-1072, 1968;.
7 +
Pfitzer P, Müntefering H:  Chromosomentranslokation bei familiär gehäufter Cyclopie . Virchows Arch 1:323-341, 1968;.
8 +
Marin-Padilla M:  Study of the skull in human cranioschisis . Acta Anat 62:1-20, 1965;.
9 +
Warkany J, Takacs E:  Experimental production of congenital malformation in rats by salicylate poisoning . Am J Path 35:315-331, 1959;.
10 +
Larsson KS:  Action of salicylate on prenatal development , in Tuchmann-Duplessis H (ed): Malformation Congénitales des Mammifères . Paris, Masson et Cie, 1971;, pp 171-186.
11 +
Wilson, JG:  Use of primates in teratological reserarch and testing , in Tuchmann-Duplessis H (ed): Malformation Congénitales des Mammifères . Paris, Masson et Cie, 1971;, pp 273-290.
12 +
Walker BE:  Induction of cleft palate in rats with antiinflammatory drugs . Teratology 4:39-42, 1971;.
13 +
Sever JL:  Virus infections and malformation . Fed Proc 30:114-117, 1971;.
14 +
Hakosalo J, Sáxen L:  Influenza epidemic and congenital defects . Lancet 2:1346-1347, 1971;.
15 +
Edmonds HW:  Pituitary adrenal and thyroid in cylopia . Arch Path 1:727-735, 1960;.
16 +
Brewer DB:  Congenital absence of the pituitary and its consequences . J Path Bact 73:59-67, 1957;.
17 +
Assche FA, Gepts W, De Gasparo M:  The endocrine pancreas in anencephalics: A histological, histochemical and biological study . Biol Neonate 14:374-388, 1969;.

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References

1 +
Lilliard RL:  The cyclop deformity . Rocky Mt Med J 61:32-34, (Dec) 1964;.
2 +
Arakaki DI, Waxman SH:  Trisomy-D in cyclops . J Pediatr 74:620-625, 1969;.
3 +
Toews HA, Jones HW:  Cyclopia in association with D-trisomy and gonadal agenesis . Am J Obstet Gynecol 102:53-56, 1968;.
4 +
Halbrecht I, et al:  Trisomy-D in cyclops . Obstet Gynecol 37:391-393, 1971;.
5 +
Schval AR:  Recent progress in human chromosome analysis and its relation to the sex chromatin . Am J Med 31:397-441, 1961;.
6 +
Pfitzer P, Müntefering H:  Cyclopism as a hereditary malformation . Nature 217:1071-1072, 1968;.
7 +
Pfitzer P, Müntefering H:  Chromosomentranslokation bei familiär gehäufter Cyclopie . Virchows Arch 1:323-341, 1968;.
8 +
Marin-Padilla M:  Study of the skull in human cranioschisis . Acta Anat 62:1-20, 1965;.
9 +
Warkany J, Takacs E:  Experimental production of congenital malformation in rats by salicylate poisoning . Am J Path 35:315-331, 1959;.
10 +
Larsson KS:  Action of salicylate on prenatal development , in Tuchmann-Duplessis H (ed): Malformation Congénitales des Mammifères . Paris, Masson et Cie, 1971;, pp 171-186.
11 +
Wilson, JG:  Use of primates in teratological reserarch and testing , in Tuchmann-Duplessis H (ed): Malformation Congénitales des Mammifères . Paris, Masson et Cie, 1971;, pp 273-290.
12 +
Walker BE:  Induction of cleft palate in rats with antiinflammatory drugs . Teratology 4:39-42, 1971;.
13 +
Sever JL:  Virus infections and malformation . Fed Proc 30:114-117, 1971;.
14 +
Hakosalo J, Sáxen L:  Influenza epidemic and congenital defects . Lancet 2:1346-1347, 1971;.
15 +
Edmonds HW:  Pituitary adrenal and thyroid in cylopia . Arch Path 1:727-735, 1960;.
16 +
Brewer DB:  Congenital absence of the pituitary and its consequences . J Path Bact 73:59-67, 1957;.
17 +
Assche FA, Gepts W, De Gasparo M:  The endocrine pancreas in anencephalics: A histological, histochemical and biological study . Biol Neonate 14:374-388, 1969;.

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