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Cerebral Arteriovenous Fistula With Possible Hereditary Telangiectasia

Ragna C. Boynton, MD; Beverly C. Morgan, MD
Am J Dis Child. 1973;125(1):99-101. doi:10.1001/archpedi.1973.04160010065014.
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A newborn infant with a family history of hereditary hemorrhagic telangiectasia (HHT) had congestive heart failure secondary to a large intracerebral arteriovenous (AV) malformation. The patient's father had had an angiomatous malformation removed from the spinal cord. Although there is no way to demonstrate conclusively that the infant is a carrier of HHT, the known occurrence of AV fistulas in the lungs of infants later demonstrated to have the disease, as well as the manifestation of smaller cerebral lesions in later life in HHT patients, suggest that the large cerebral malformation in this case was related to the strong family history of HHT. Knowledge of the possibility of such an association might speed the diagnosis and treatment of these otherwise often undetected and frequently fatal malformations.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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