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November 1972, Vol 124, No. 5 >
Article | November 1972

Transient Murmur Simulating Pulmonary Artery Stenosis in Premature Infants FREE

Lisa M. Dunkle, MD; Richard D. Rowe, MD, FRCP
[+] Author Affiliations

Received for publication Feb 7, 1972; accepted June 7.

Reprint requests to Children's Medical and Surgical Center, Johns Hopkins Hospital, 601 N Broadway, Baltimore 21205 (Dr. Rowe).


Am J Dis Child. 1972;124(5):666-670. doi:10.1001/archpedi.1972.02110170044006.
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References
Comments

The incidence of a transient murmur resembling that of pulmonary arterial stenosis in healthy premature infants during the first six weeks of life was 67% (ten of 15) whereas only 5% of term infants (three of 61) were noted to have such a murmur during the few days spent in hospital. None of 25 term infants examined at home during the first four weeks of life had the murmur.

The murmur was most frequently seen in babies with a birth weight below 2,200 gm (5 lb).

Hypoplasia of the pulmonary artery branches or unusual alignment of the main pulmonary artery with its branches in premature infants are postulated as causes of the murmur which disappears as the infant grows.

REFERENCES

1 +
Eldridge F, Selzer A, Hultgren H:  Stenosis of a branch of the pulmonary artery: An additional cause of continuous murmurs over the chest . Circulation 15:865-874, 1957;.
2 +
Keith JD, Rowe RD, Vlad P: Heart Disease in Infancy and Childhood . New York, Macmillan Co, 1967;, pp 584-597.
3 +
Wasserman WB, Varghese PJ, Rowe RD:  The evolution of pulmonary artery stenosis associated with congenital rubella . Am Heart J 76:638-644, 1968;.
4 +
Danilowicz DA, et al:  Physiologic pressure differences between main and branch pulmonary arteries in infants . Circulation 45:410-419, 1972;.
5 +
Patten BM:  The changes in the circulation following birth . Am Heart J 6:192-205, 1930;.
6 +
Rowe RD, Mehrizi A: The Neonate with Congenital Heart Disease . Philadelphia, WB Saunders Co, 1968;, p 26.
7 +
Braudo M, Rowe RD:  Auscultation of the heart—early neonatal period . Am J Dis Child 101:575-586, 1961;.
8 +
Craige E, Harned HS Jr:  Phonocardiographic and electrocardiographic studies in normal newborn infants . Am Heart J 65:180-189, 1963;.
9 +
Hallidie-Smith KA:  Some auscultatory and phonocardiographic findings observed in early infancy . Br Med J 1:756-759, 1960;.
10 +
Naeye RL:  Arterial changes during the perinatal period . Arch Path 71:121-128, 1961;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Eldridge F, Selzer A, Hultgren H:  Stenosis of a branch of the pulmonary artery: An additional cause of continuous murmurs over the chest . Circulation 15:865-874, 1957;.
2 +
Keith JD, Rowe RD, Vlad P: Heart Disease in Infancy and Childhood . New York, Macmillan Co, 1967;, pp 584-597.
3 +
Wasserman WB, Varghese PJ, Rowe RD:  The evolution of pulmonary artery stenosis associated with congenital rubella . Am Heart J 76:638-644, 1968;.
4 +
Danilowicz DA, et al:  Physiologic pressure differences between main and branch pulmonary arteries in infants . Circulation 45:410-419, 1972;.
5 +
Patten BM:  The changes in the circulation following birth . Am Heart J 6:192-205, 1930;.
6 +
Rowe RD, Mehrizi A: The Neonate with Congenital Heart Disease . Philadelphia, WB Saunders Co, 1968;, p 26.
7 +
Braudo M, Rowe RD:  Auscultation of the heart—early neonatal period . Am J Dis Child 101:575-586, 1961;.
8 +
Craige E, Harned HS Jr:  Phonocardiographic and electrocardiographic studies in normal newborn infants . Am Heart J 65:180-189, 1963;.
9 +
Hallidie-Smith KA:  Some auscultatory and phonocardiographic findings observed in early infancy . Br Med J 1:756-759, 1960;.
10 +
Naeye RL:  Arterial changes during the perinatal period . Arch Path 71:121-128, 1961;.

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