Clinical History.—This 10½-year-old girl was first seen as an outpatient in December 1970. She had a history of recurrent urinary tract infections which, in two instances, were well documented by laboratory studies. She also had a history of enuresis during the past four months. There was no dysuria or hematuria. At 2 to 3 years of age there were several episodes of unexplained fever.
There has been no renal disease in the family but there are two cases of diabetes on the maternal side and the paternal grandmother has multiple sclerosis. The remainder of the history was noncontributory.
Physical Examination.—The child was below the third percentile in height and at the fifth percentile in weight. Blood pressure was 110/76 mm Hg. There were no abnormal findings.
Laboratory Studies.—Results of urinalysis: pH, 5.0; specific gravity, 1.013; no glucose or albumin. The microscope showed 3 to 5 white blood