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June 1972, Vol 123, No. 6 >
Article | June 1972

STAPHYLOCOCCUS 502A FREE

WERNER N, KEIDEL, MD
Am J Dis Child. 1972;123(6):613. doi:10.1001/archpedi.1972.02110120137029.
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To the Editor.—Houck et al1 recently reported the complications of bacterial interference programs using Staphylococcus aureus 502A. Thirty-eight (5.9%) of the 644 deliberately colonized infants developed disease related to the 502A strain. One infant with an umbilical catheter developed a fatal septicemia. A second infant developed an abscess when a "superficial abrasion" of the left great toe became infected. And yet, the authors concluded from their study that S aureus 502A was a safe and effective means of aborting staphylococcal epidemics. They did mention the risk of using bacterial interference techniques for certain groups of infants—premature infants and those with umbilical catheters. As these and other infants at high risk for infection make up the usual population of an intensive care nursery (ICN), S aureus 502A may pose a considerable risk if used there.

Hexachlorophene bathing of the newborn and strict handwashing techniques have markedly decreased the incidence

REFERENCES

1 +
Houck PW, Nelson JD, Kay JL:  Fatal septicemia due to Staphylococcus aureus 502A: Report of a Case and Review of the Infectious Complications of Bacterial Interference Programs . Amer J Dis Child 123:45-48, 1972;.
2 +
Forfar JO, Gould JC, MacCabe AF:  Effect of hexachlorophene on incidence of staphylococal and gram-negative infection in the newborn . Lancet 2:177-180, 1968;.
Link to Article
3 +
Gluck L, Wood HF:  Staphylococcal colonization in newborn infants with and without antiseptic skin care . New Eng J Med 268:1265-1268, 1963;.
Link to Article
4 +
Simon HJ, Yaffe SJ, Gluck L:  Effective control of staphylococci in a nursery . New Eng J Med 265:1171-1176, 1961;.
Link to Article
5 +
Kimbrough RD, Gaines TB:  Hexachlorophene effects on the rat brain . Arch Environ Health 23:114-118, 1971;.
Link to Article
6 +
Hexachlorophene and skin care of newborns. Newsletter supplement Jan 1, 1972. Committee Statement, Committee on Fetus and Newborn, American Academy of Pediatrics.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Houck PW, Nelson JD, Kay JL:  Fatal septicemia due to Staphylococcus aureus 502A: Report of a Case and Review of the Infectious Complications of Bacterial Interference Programs . Amer J Dis Child 123:45-48, 1972;.
2 +
Forfar JO, Gould JC, MacCabe AF:  Effect of hexachlorophene on incidence of staphylococal and gram-negative infection in the newborn . Lancet 2:177-180, 1968;.
Link to Article
3 +
Gluck L, Wood HF:  Staphylococcal colonization in newborn infants with and without antiseptic skin care . New Eng J Med 268:1265-1268, 1963;.
Link to Article
4 +
Simon HJ, Yaffe SJ, Gluck L:  Effective control of staphylococci in a nursery . New Eng J Med 265:1171-1176, 1961;.
Link to Article
5 +
Kimbrough RD, Gaines TB:  Hexachlorophene effects on the rat brain . Arch Environ Health 23:114-118, 1971;.
Link to Article
6 +
Hexachlorophene and skin care of newborns. Newsletter supplement Jan 1, 1972. Committee Statement, Committee on Fetus and Newborn, American Academy of Pediatrics.

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