0
Article |

Platelet Aggregation Test in the Study of Hepatitis

Kari Penttinen, MD
Am J Dis Child. 1972;123(4):418-420. doi:10.1001/archpedi.1972.02110100150058.
Text Size: A A A
Published online

The platelet aggregation test (PLA) can be used as an indicator of Australia antigen or antibody in the serum.1,2 The reaction of Au antigen-Au antibody complexes with human platelets changes the pattern of sedimentation of platelets on microplates.2 This method has also been used to detect other antibodies and antigens.3 When PLA was used to study hepatitis sera, it was soon found that many of these sera reacted directly with platelets without any added antibody or antigen. Earlier studies show that this can be a sign of the presence of immune complexes in the blood.4 The possibility of immune complexes in severe hepatitis cases has recently been under special consideration.5 This paper presents the results of 93 cases of different forms of hepatitis, 49 other diseases, and 99 blood donors. Special consideration is given to the "direct" reactivity of sera. The detection of the

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();