We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Monographs in Paediatrics, Vol 1, Congenital Disorders of the Urea Cycle and Ammonia Detoxication.

Am J Dis Child. 1972;123(2):184. doi:10.1001/archpedi.1972.02110080162031.
Text Size: A A A
Published online


This monograph provides a unique survey of congenital disorders of the ammonia metabolism. The author deserves special praise for the discussion of prenatal development of fetal ammonia metabolism comprising one third of the book, and also for presenting a wealth of new data. Although it is uncommon nowadays to publish research data in book form, the complete presentation of this information in connection with clinical material is very beneficial. Thus the author provides us with a solid foundation for pathogenetic considerations, diagnostic studies, and therapeutic measures. Discrepancies concerning the ammonia blood levels in normal and pathologic states are clearly spelled out, and the author's own experiments seem to clarify contradictions in older studies. The composition of free amino acids has been analyzed not only in blood, urine, and cerebrospinal fluid of patients but also in normal fetal brain. A series of good graphic presentations and the frequent use of headings


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.