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Juvenile Papilloma of the Larynx FREE

James M. Oleske; Theodore Kushnick, MD
[+] Author Affiliations

Received for publication Dec 31, 1970.

Reprint requests to 100 Bergen St, Newark, NJ 07103 (Dr. Kushnick).


Am J Dis Child. 1971;121(5):417-419. doi:10.1001/archpedi.1971.02100160087011.
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A two-year-old Negro-South American girl presented with juvenile laryngeal papilloma which necessitated an emergency tracheostomy. During the next 1½ years of hospitalization, she required general anesthesia for surgical excision of recurrent growths on an average of once every 3.7 weeks. Inasmuch as the process continued unabated, autogenous vaccine prepared from her tumor was administered by 15 weekly injections. There was an apparent dramatic beneficial response with vocalization around the tracheostomy tube occurring for the first time within two months of the start of vaccine therapy. Tumor growth regressed completely, the tracheostomy tube was removed within six months of the utilization of vaccine treatment and the patient was discharged after two years of hospitalization.

REFERENCES

Ferguson CF, Scott HW Jr:  Papilloma of larynx in childhood . New Eng J Med 230:477-482, 1944;.
Holinger PH, Shipkowitz NL, Holper JC, et al:  Studies of etiology of laryngeal papilloma and autogenous laryngeal papilloma vaccine . Acta Otolaryng 65:63-69, 1968;.
Newberg LJ, High HC, Lehman RH, et al:  Fatality from juvenile laryngeal papilloma . Arch Otolaryng 86:681-684, 1967;.
Majoros M, Parkhill EM, Devine KD:  Papilloma in the larynx in children . Amer J Surg 108:470-475, 1964;.
Holinger PH, Schild JA, Maurizi DG:  Laryngeal papilloma: Review of etiology and therapy . Laryngoscope 78:1462-1474, 1968;.
Shipkowitz NL, Holinger PH, Holper JG, et al:  Evaluation of autogenous laryngeal papilloma vaccine . Laryngoscope 77:1047-1053, 1967;.
Strome M:  Analysis of an autogenous vaccine in treatment of juvenile papilloma . Laryngoscope 79:272-279, 1969;.
Gross CW, Crocker TR:  Current management of juvenile laryngeal papillomata . Laryngoscope 80:523-543, 1970;.
Hellstrom KE, Hellstrom I:  Cellular immunity against tumor antigen . Advances Cancer Res 12:167-223, 1969;.
Jehn UW, Nathanson L, Schwartz RS, et al:  Lymphocyte stimulation by soluble antigen from malignant melanoma . New Eng J Med 283:329-333, 1970;.
Cooper HL:  Lymphocyte stimulation in malignant melanoma . New Eng J Med 283:369-370, 1970;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Ferguson CF, Scott HW Jr:  Papilloma of larynx in childhood . New Eng J Med 230:477-482, 1944;.
Holinger PH, Shipkowitz NL, Holper JC, et al:  Studies of etiology of laryngeal papilloma and autogenous laryngeal papilloma vaccine . Acta Otolaryng 65:63-69, 1968;.
Newberg LJ, High HC, Lehman RH, et al:  Fatality from juvenile laryngeal papilloma . Arch Otolaryng 86:681-684, 1967;.
Majoros M, Parkhill EM, Devine KD:  Papilloma in the larynx in children . Amer J Surg 108:470-475, 1964;.
Holinger PH, Schild JA, Maurizi DG:  Laryngeal papilloma: Review of etiology and therapy . Laryngoscope 78:1462-1474, 1968;.
Shipkowitz NL, Holinger PH, Holper JG, et al:  Evaluation of autogenous laryngeal papilloma vaccine . Laryngoscope 77:1047-1053, 1967;.
Strome M:  Analysis of an autogenous vaccine in treatment of juvenile papilloma . Laryngoscope 79:272-279, 1969;.
Gross CW, Crocker TR:  Current management of juvenile laryngeal papillomata . Laryngoscope 80:523-543, 1970;.
Hellstrom KE, Hellstrom I:  Cellular immunity against tumor antigen . Advances Cancer Res 12:167-223, 1969;.
Jehn UW, Nathanson L, Schwartz RS, et al:  Lymphocyte stimulation by soluble antigen from malignant melanoma . New Eng J Med 283:329-333, 1970;.
Cooper HL:  Lymphocyte stimulation in malignant melanoma . New Eng J Med 283:369-370, 1970;.

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