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February 1971, Vol 121, No. 2 >
Article | February 1971

Preoperative Detection of Hidden Testes FREE

Lenore S. Levine, MD; Maria I. New, MD
[+] Author Affiliations

Received for publication July 9, 1970.

Reprint requests to the New York Hospital-Cornell Medical Center, 525 E 68th St, New York 10021 (Dr. Levine).


Am J Dis Child. 1971;121(2):176-178. doi:10.1001/archpedi.1971.02100130130017.
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A method for detecting occult Leydig cell tissue of the testis utilizes the determination of plasma testosterone or testosterone production before and after administration of chorionic gonadotropin. The method was applied successfully to the detection of testes in a boy with bilateral cryptorchidism, who had been unsuccessfully explored for testes, and in a true hermaphrodite. It is recommended that testosterone determinations after chorionic gonadotropin be applied to detect testes in prepubertal children with bilateral cryptorchidism, testicular feminization, and ambiguous genitalia.

REFERENCES

1 +
Robinson JN, Engle ET:  Some observations in the cryptorchid testis . J Urol 71:726-734, 1954;.
2 +
New MI, Gross JM, Peterson RE:  A double isotope dilution derivative technique for testosterone glucuronoside in urine . Acta Endocr 58:77-97,1968;.
3 +
New MI, Miller B, Peterson RE:  Aldosterone excretion in normal children and in children with adrenal hyperplasia . J Clin Invest 45:412-428, 1966;.
4 +
Frasier SD, Gafford F, Horton R:  Plasma androgens in childhood and adolescence . J Clin Endocr 29:1404-1408, 1969;.
5 +
Saez JM, Bertrand J:  Studies on testicular function in children: Plasma concentrations of testosterone, dehydroepiandrosterone and its sulfate before and after stimulation with human chorionic gonadotrophin . Steroids 12:749-761, 1968;.
6 +
Hudson B, Coghlan JP, Dulmanis A, et al:  The measurement of testosterone in biological fluids in the evaluation of androgen activity: Second International Congress of Endocrinology , London. Excerpta Medica 83:1127-1134, 1965;.
7 +
Kirschner MA, Jacobs BJ, Fraley EE:  Bilateral anorchia with persistent testosterone production . New Eng J Med 282:240-244, 1970;.
8 +
Lipsett MB, Migeon CJ, Kirschner MA, et al:  Physiologic basis of disorders of androgen metabolism: Combined clinical staff conference at the National Institutes of Health . Ann Intern Med 68:1327-1344, 1968;.

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References

1 +
Robinson JN, Engle ET:  Some observations in the cryptorchid testis . J Urol 71:726-734, 1954;.
2 +
New MI, Gross JM, Peterson RE:  A double isotope dilution derivative technique for testosterone glucuronoside in urine . Acta Endocr 58:77-97,1968;.
3 +
New MI, Miller B, Peterson RE:  Aldosterone excretion in normal children and in children with adrenal hyperplasia . J Clin Invest 45:412-428, 1966;.
4 +
Frasier SD, Gafford F, Horton R:  Plasma androgens in childhood and adolescence . J Clin Endocr 29:1404-1408, 1969;.
5 +
Saez JM, Bertrand J:  Studies on testicular function in children: Plasma concentrations of testosterone, dehydroepiandrosterone and its sulfate before and after stimulation with human chorionic gonadotrophin . Steroids 12:749-761, 1968;.
6 +
Hudson B, Coghlan JP, Dulmanis A, et al:  The measurement of testosterone in biological fluids in the evaluation of androgen activity: Second International Congress of Endocrinology , London. Excerpta Medica 83:1127-1134, 1965;.
7 +
Kirschner MA, Jacobs BJ, Fraley EE:  Bilateral anorchia with persistent testosterone production . New Eng J Med 282:240-244, 1970;.
8 +
Lipsett MB, Migeon CJ, Kirschner MA, et al:  Physiologic basis of disorders of androgen metabolism: Combined clinical staff conference at the National Institutes of Health . Ann Intern Med 68:1327-1344, 1968;.

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