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February 1971, Vol 121, No. 2 >
Article | February 1971

Chediak-Higashi Syndrome in a Child with Hodgkin's Disease FREE

Charlotte Tan, MD; Erlinda Etcubanas, MD; Philip Lieberman, MD; Hazel Isenberg; Oscar King, MD; M. Lois Murphy, MD
[+] Author Affiliations

Received for publication Oct 26,1970.

Reprint requests to Memorial Sloan-Kettering Cancer Center, 444 E 68th St, New York 10021 (Dr. Tan).


Am J Dis Child. 1971;121(2):135-139. doi:10.1001/archpedi.1971.02100130089010.
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References
Comments

Hodgkin's disease developed in a girl 8 years 9 months of age with the physical and hematologic stigmata of Chediak-Higashi syndrome. The association of malignant lymphoma with Chediak-Higashi syndrome has been reported previously, but to our knowledge, no case of Hodgkin's disease has been described to date.

REFERENCES

1 +
Beguez-Cesar A:  Neutropenia cronica maligna familiar con granulaciones atipicas de los leucocitos . Bol Soc Cub Pediat 15:900, 1943;.
2 +
Steinbrinck W:  Über eine Neve Granulations-Anomalie der Leukocyten . Deutsch Arch Klin Med 193:577, 1948;.
3 +
Chediak M:  Nouvelle anomalie leucocytaire de caractere constitutional et familia . Rev Hemat 7:362, 1952;.
4 +
Higashi O:  Congenital gigantism of peroxidase granules . Tohoku J Exp Med 59:315, 1954;.
5 +
Dent PB, Fish LA, White JG, et al:  Chediak-Higashi syndrome: Observations on the nature of the associated malignancy . Lab Invest 15:1634-1642, 1966;.
6 +
Leader RT, Padgett GA, Gorham JR:  Studies of abnormal leucocyte bodies in mink . Blood 22:477-484, 1963;.
7 +
Padgett GA, Leader RW, Gorham JR, et al:  The familial occurrence of the Chediak-Higashi syndrome in mink and cattle . Genetics 49:505, 1964;.
8 +
Lutzner MA, Lourie CT, Jordan HW:  Giant granules in leucocytes of the beige mouse . J Hered 58:299, 1967;.
9 +
Padgett GA, Reiquam CW, Gorham JR, et al:  Comparative studies of the Chediak-Higashi syndrome . Amer J Path 51:553-571, 1967;.
10 +
Windhorst DB, Zelickson AS, Good RA:  A human pigmentary dilution based on a heritable subcellular structural defect, the Chediak-Higashi syndrome . J Invest Derm 50:9-18,1965;.
11 +
Zelickson AS, Windhorst DB, White JG, et al:  The Chediak-Higashi syndrome: Formation of giant melanosomes and the basis of hypopigmentation . J Invest Derm 49:575-581, 1967;.
12 +
Bedoya V, Grimley PM, Duque O:  Chediak-Higashi syndrome . Arch Path 88:340-349, 1969;.
13 +
Mauri C, Silingardi V:  A cytological and cytochemical study of Chediak's leukocytic anomaly . Acta Haemat 33:114-126, 1964;.
14 +
White JG:  The Chediak-Higashi syndrome: Cytoplasmic sequestration in circulating leukocytes . Blood 33:821-832, 1969;.
15 +
Bennett JM, Blume RS, Wolff SM:  Characterization and significance of abnormal leukocyte granules in the beige mouse: A possible homologue for Chediak-Higashi Aleutian trait . J Lab Clin Med 73:235-243, 1969;.
16 +
Page AR, Berendes H, Warner J, et al:  The Chediak-Higashi syndrome . Blood 20:330-343, 1962;.

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References

1 +
Beguez-Cesar A:  Neutropenia cronica maligna familiar con granulaciones atipicas de los leucocitos . Bol Soc Cub Pediat 15:900, 1943;.
2 +
Steinbrinck W:  Über eine Neve Granulations-Anomalie der Leukocyten . Deutsch Arch Klin Med 193:577, 1948;.
3 +
Chediak M:  Nouvelle anomalie leucocytaire de caractere constitutional et familia . Rev Hemat 7:362, 1952;.
4 +
Higashi O:  Congenital gigantism of peroxidase granules . Tohoku J Exp Med 59:315, 1954;.
5 +
Dent PB, Fish LA, White JG, et al:  Chediak-Higashi syndrome: Observations on the nature of the associated malignancy . Lab Invest 15:1634-1642, 1966;.
6 +
Leader RT, Padgett GA, Gorham JR:  Studies of abnormal leucocyte bodies in mink . Blood 22:477-484, 1963;.
7 +
Padgett GA, Leader RW, Gorham JR, et al:  The familial occurrence of the Chediak-Higashi syndrome in mink and cattle . Genetics 49:505, 1964;.
8 +
Lutzner MA, Lourie CT, Jordan HW:  Giant granules in leucocytes of the beige mouse . J Hered 58:299, 1967;.
9 +
Padgett GA, Reiquam CW, Gorham JR, et al:  Comparative studies of the Chediak-Higashi syndrome . Amer J Path 51:553-571, 1967;.
10 +
Windhorst DB, Zelickson AS, Good RA:  A human pigmentary dilution based on a heritable subcellular structural defect, the Chediak-Higashi syndrome . J Invest Derm 50:9-18,1965;.
11 +
Zelickson AS, Windhorst DB, White JG, et al:  The Chediak-Higashi syndrome: Formation of giant melanosomes and the basis of hypopigmentation . J Invest Derm 49:575-581, 1967;.
12 +
Bedoya V, Grimley PM, Duque O:  Chediak-Higashi syndrome . Arch Path 88:340-349, 1969;.
13 +
Mauri C, Silingardi V:  A cytological and cytochemical study of Chediak's leukocytic anomaly . Acta Haemat 33:114-126, 1964;.
14 +
White JG:  The Chediak-Higashi syndrome: Cytoplasmic sequestration in circulating leukocytes . Blood 33:821-832, 1969;.
15 +
Bennett JM, Blume RS, Wolff SM:  Characterization and significance of abnormal leukocyte granules in the beige mouse: A possible homologue for Chediak-Higashi Aleutian trait . J Lab Clin Med 73:235-243, 1969;.
16 +
Page AR, Berendes H, Warner J, et al:  The Chediak-Higashi syndrome . Blood 20:330-343, 1962;.

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