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Survival of Patients With Cystic Fibrosis

Nancy N. Huang, MD; Carlos N. Macri, MD; Joseph Girone, MD; Ann Sproul, MD
Am J Dis Child. 1970;120(4):289-295. doi:10.1001/archpedi.1970.02100090063002.
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The survival rates of patients with cystic fibrosis admitted in three five-year periods, July 1952 to June 1967, are compared. The "life table method" was adopted to compute the survival rates. The three cohorts included 37 patients admitted between July 1952 and June 1957 (group 1), 73 between July 1957 and June 1962 (group 2), and 129 between July 1962 and June 1967 (group 3). The five-year cumulative survival rates were 35.0% ± 8.7% for group 1, 63.6% ± 6.4% for group 2, and 76.6% ± 7.0% for group 3. Early diagnosis and early institution of therapy are important. Control of infection by use of appropriate antibiotics, emphasis on bronchial drainage, a well organized home care program, and frequent evaluations by competent physicians all contribute toward a brighter outlook for patients with cystic fibrosis.

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