A preschool communication screening program was conducted in Montgomery County, Maryland. Advertisements through news media, local nursery schools and day care centers, and local physicians urged parents to bring children suspected of having speech, hearing, or visual disorders of any etiology for examination. Blood specimens were obtained from most of the children examined and rubella hemagglutination inhibition (HI) antibody determinations were performed on the sera. From the 52 children born in 1964, the year of the last rubella epidemic, 41 sera were obtained. Rubella HI antibody was found in five, and four of these children were found upon further examination to have clinical signs consistent with the congenital rubella syndrome. Congenital rubella had not been previously diagnosed in three of these four children.