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March 1970, Vol 119, No. 3 >
Article | March 1970

Childhood Sarcoidosis Involving Joints and Kidneys FREE

Arturo Bautista, MD
[+] Author Affiliations

Received for publication April 23, 1969.

Reprint requests to the Department of Pediatrics, University of Kentucky Medical Center, Lexington, Ky 40506 (Dr. W. E. Wheeler).


Am J Dis Child. 1970;119(3):259-263. doi:10.1001/archpedi.1970.02100050261016.
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References
Comments

So uncommon are some diseases and atypical their manifestations that failure to appreciate them and recognize their importance may lead to unduly prolonged studies, unnecessary treatment, or irreversible damage. Sarcoidosis is such a disease.

Sarcoidosis, a nonspecific syndrome characterized by "the presence, in any organ or tissue, of epithelioid cells and tubercles with inconspicuous necrosis or without necrosis, and by a chronic course," is uncommon among children. Though there are over 200 cases reported in patients under 15 years of age, this number is only a small proportion of the number of cases in adults.1-8

Patients with childhood sarcoidosis frequently have clinical features that are different from those seen in adults.8,9 Even though transient polyarthritis has been reported in from 6% to 25% of adult patients,7,9-12 it occurs only rarely in children. North and co-workers17,18 compiled four such cases from the literature13-16 and added six

REFERENCES

1 +
Jaspar PL, Denny FW:  Sarcoidosis in children . J Pediat 73:499-512, 1968;.
2 +
McGovern JP, Merrit DH:  Sarcoidosis in childhood . Advances Pediat 8:97-135, 1956;.
3 +
Mandi L, Kelemen J:  Thoracic sarcoidosis in childhood . Acta Med Scand , (suppl 425) , p 135, 1964;.
4 +
Kendig EL Jr:  Sarcoidosis among children . J Pediat 61:269-278, 1962;.
5 +
Beier FR, Lahey ME:  Sarcoidosis among children in Utah and Idaho . J Pediat 65:350-359, 1964;.
6 +
Niity Y, Watanaba M, Suetake T, et al:  Sixteen cases of intrathoracic sarcoidosis found among school children in Sendai in mass x-ray surveys of the chest . Sci Rep Res Pediat Res Inst 12:99-121, 1965;.
7 +
Mayock RL, Bertrand P, Morrison C, et al:  Review: Manifestations of sarcoidosis . Amer J Med 35:67-89, 1963;.
8 +
Siltzbach LE, Greenberg G:  Childhood sarcoidosis: A study of 18 patients . New Eng J Med 279:1239-1245, 1968;.
9 +
Scadding JG: Sarcoidosis . London, Eyre and Spottiswoode Ltd, 1967;.
10 +
Sokologg L, Bunim JJ:  Clinical and pathological studies of joint involvement in sarcoidosis . New Eng J Med 260:841-847, 1959;.
11 +
Mainley KA, Shulman LE:  Joint involvement in sarcoidosis . Arthritis Rheum 3:453-454, 1960;.
12 +
Kaplan H:  Sarcoid arthritis . Arch Intern Med 112:924-935, 1963;.
13 +
Castellanos A, Galan E:  Sarcoidosis (Besnier, Boeck, Shuman's disease): Report of a case in a child simulating Still's disease . Amer J Dis Child 71:513-529, 1946;.
14 +
Burman MS, Mayer L:  Arthroscopic examination of the knee joint: Report of cases observed in the course of arthroscopic examination including instances of sarcoid and multiple polypoid fibromatosis . Arch Surg 32:846-874, 1936;.
15 +
Zweifel von E:  Gleichzeitiges vorkommen eines Boeckschen Sarkoids mit einer primaren chronischen Polyarthritis . Helv Paediat Acta 1:475-484, 1946;.
16 +
Schweitzer AT, Kanaar P:  Sarcoidosis with polyarthritis in a child . Arch Dis Child 42:671-674, 1968;.
17 +
North AF Jr, et al:  Rare diagnosis: Sarcoid arthritis in four children . JAMA 197:1, 1966;.
18 +
North AF Jr, et al: Sarcoid arthritis in children: A clinical syndrome?, to be published.
19 +
Berger KW, Arnold SR:  Renal impairment due to sarcoid infiltration of the kidney: Report of a case proved by renal biopsies before and after treatment with cortisone . New Eng J Med 252:44-49, 1955;.
20 +
McDonald CH:  Renal sarcoidosis . J Clin Path 9:136-141, 1956;.
21 +
Cantwell DF:  Sarcoidosis with renal involvement . Irish J Med Sci 6:223-229, 1954;.
22 +
Keech MR:  Generalized sarcoidosis with renal involvement . Proc Roy Soc Med 44:728-829, 1951;.
23 +
Kogut DM, Newman LL:  Renal involvement in Boeck's sarcoidosis . Pediat 28:410-424, 1961;.
24 +
Putkonen T, Virkkunken M, Wager D:  Joint involvement in sarcoidosis with special reference to sarcoid arthritis and rheumatoid arthritis . Acta Rheum Scand 11:53-61, 1965;.
25 +
Longcope TW, Freeman CD:  A study of sarcoidosis . Medicine 31:1, 132, 1952;.
26 +
Telun G:  Morphogenesis and development of sarcoid lesions: Similarity to the group of collageneous diseases . Acta Med Scand (suppl 425) , p 14, 1964;.
27 +
Correa P:  Sarcoidosis: Association with glomerulonephritis . Arch Path 57: 523-529, 1954;.
28 +
Siltzbach LE:  The enigma of sarcoidosis . Hosp Pract 3:80-91, 1968;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Jaspar PL, Denny FW:  Sarcoidosis in children . J Pediat 73:499-512, 1968;.
2 +
McGovern JP, Merrit DH:  Sarcoidosis in childhood . Advances Pediat 8:97-135, 1956;.
3 +
Mandi L, Kelemen J:  Thoracic sarcoidosis in childhood . Acta Med Scand , (suppl 425) , p 135, 1964;.
4 +
Kendig EL Jr:  Sarcoidosis among children . J Pediat 61:269-278, 1962;.
5 +
Beier FR, Lahey ME:  Sarcoidosis among children in Utah and Idaho . J Pediat 65:350-359, 1964;.
6 +
Niity Y, Watanaba M, Suetake T, et al:  Sixteen cases of intrathoracic sarcoidosis found among school children in Sendai in mass x-ray surveys of the chest . Sci Rep Res Pediat Res Inst 12:99-121, 1965;.
7 +
Mayock RL, Bertrand P, Morrison C, et al:  Review: Manifestations of sarcoidosis . Amer J Med 35:67-89, 1963;.
8 +
Siltzbach LE, Greenberg G:  Childhood sarcoidosis: A study of 18 patients . New Eng J Med 279:1239-1245, 1968;.
9 +
Scadding JG: Sarcoidosis . London, Eyre and Spottiswoode Ltd, 1967;.
10 +
Sokologg L, Bunim JJ:  Clinical and pathological studies of joint involvement in sarcoidosis . New Eng J Med 260:841-847, 1959;.
11 +
Mainley KA, Shulman LE:  Joint involvement in sarcoidosis . Arthritis Rheum 3:453-454, 1960;.
12 +
Kaplan H:  Sarcoid arthritis . Arch Intern Med 112:924-935, 1963;.
13 +
Castellanos A, Galan E:  Sarcoidosis (Besnier, Boeck, Shuman's disease): Report of a case in a child simulating Still's disease . Amer J Dis Child 71:513-529, 1946;.
14 +
Burman MS, Mayer L:  Arthroscopic examination of the knee joint: Report of cases observed in the course of arthroscopic examination including instances of sarcoid and multiple polypoid fibromatosis . Arch Surg 32:846-874, 1936;.
15 +
Zweifel von E:  Gleichzeitiges vorkommen eines Boeckschen Sarkoids mit einer primaren chronischen Polyarthritis . Helv Paediat Acta 1:475-484, 1946;.
16 +
Schweitzer AT, Kanaar P:  Sarcoidosis with polyarthritis in a child . Arch Dis Child 42:671-674, 1968;.
17 +
North AF Jr, et al:  Rare diagnosis: Sarcoid arthritis in four children . JAMA 197:1, 1966;.
18 +
North AF Jr, et al: Sarcoid arthritis in children: A clinical syndrome?, to be published.
19 +
Berger KW, Arnold SR:  Renal impairment due to sarcoid infiltration of the kidney: Report of a case proved by renal biopsies before and after treatment with cortisone . New Eng J Med 252:44-49, 1955;.
20 +
McDonald CH:  Renal sarcoidosis . J Clin Path 9:136-141, 1956;.
21 +
Cantwell DF:  Sarcoidosis with renal involvement . Irish J Med Sci 6:223-229, 1954;.
22 +
Keech MR:  Generalized sarcoidosis with renal involvement . Proc Roy Soc Med 44:728-829, 1951;.
23 +
Kogut DM, Newman LL:  Renal involvement in Boeck's sarcoidosis . Pediat 28:410-424, 1961;.
24 +
Putkonen T, Virkkunken M, Wager D:  Joint involvement in sarcoidosis with special reference to sarcoid arthritis and rheumatoid arthritis . Acta Rheum Scand 11:53-61, 1965;.
25 +
Longcope TW, Freeman CD:  A study of sarcoidosis . Medicine 31:1, 132, 1952;.
26 +
Telun G:  Morphogenesis and development of sarcoid lesions: Similarity to the group of collageneous diseases . Acta Med Scand (suppl 425) , p 14, 1964;.
27 +
Correa P:  Sarcoidosis: Association with glomerulonephritis . Arch Path 57: 523-529, 1954;.
28 +
Siltzbach LE:  The enigma of sarcoidosis . Hosp Pract 3:80-91, 1968;.

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