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NEONATAL MESENTERIC ARTERY THROMBOSIS-Reply FREE

MYRON M. NICHOLS, MD
Am J Dis Child. 1969;118(6):940. doi:10.1001/archpedi.1969.02100040942031.
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To the Editor.—I wish to thank Drs. W. J. Keenan and A. J. McAdams for their letter. Their references would indicate that steroids increase coagulability in adults. The use of hydrocortisone in the management of this infant may have been unnecessary, but it is more likely that the thrombosis resulted from the fact that the infant was an infant of a diabetic mother rather than from the use of hydrocortisone.1

Glucagon2 might have been tried or perhaps epinephrine3,4 rather than steroids, although steroids are mentioned as treatment for hypoglycemia when on repeated assay the glucose fails to rise.5

I would appreciate comments from other readers on the effects of steroids on neonatal coagulability.

REFERENCES

Oppenheimer, E.H., and Esterly, J.R.:  Thrombosis in the Newborn: Comparison Between Infants of Diabetic and Nondiabetic Mothers , J Pediat 67:549-556 ( (Oct) ) 1965;.
Gordon, H.H.:  Infants of Diabetic Mothers , Amer J Med Sci 244:129 ( (Aug) ) 1962;.
Light, I.J.:  Epinephrine Excretion in Infants of Diabetic Mothers , New Eng J Med 277:394, 1967;.
Keenan, W.J.; Light, I.J.; and Sutherland, J.M.:  Effects of Exogenous Epinephrine on Insulin Levels in Infants of Diabetic Mothers , Abstracts of Proceedings of Society for Pediatric Research , Atlantic City, NJ, p 147, (May 2) -3, 1969;, p 147.
Cornblath, M., and Schwartz, R.: Disorders of Carbohydrate Metabolism in Infancy , Philadelphia: W. B. Saunders Co., 1966;, p 77.

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References

Oppenheimer, E.H., and Esterly, J.R.:  Thrombosis in the Newborn: Comparison Between Infants of Diabetic and Nondiabetic Mothers , J Pediat 67:549-556 ( (Oct) ) 1965;.
Gordon, H.H.:  Infants of Diabetic Mothers , Amer J Med Sci 244:129 ( (Aug) ) 1962;.
Light, I.J.:  Epinephrine Excretion in Infants of Diabetic Mothers , New Eng J Med 277:394, 1967;.
Keenan, W.J.; Light, I.J.; and Sutherland, J.M.:  Effects of Exogenous Epinephrine on Insulin Levels in Infants of Diabetic Mothers , Abstracts of Proceedings of Society for Pediatric Research , Atlantic City, NJ, p 147, (May 2) -3, 1969;, p 147.
Cornblath, M., and Schwartz, R.: Disorders of Carbohydrate Metabolism in Infancy , Philadelphia: W. B. Saunders Co., 1966;, p 77.

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