0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Familial Nephritis Associated With the Nephrotic Syndrome:  In a Family With Severe Involvement in Females

Morris S. Albert, MD; Joan M. Leeming, MB, ChB; H. Joachim Wigger, MD
Am J Dis Child. 1969;117(2):153-155. doi:10.1001/archpedi.1969.02100030155006.
Text Size: A A A
Published online

THE hereditary features of renal disease have engendered considerable interest within the past few years.1,2 Foremost among the hereditary nephropathies has been the syndrome of familial nephritis.2 In the majority of the kindred with this disorder, affected males initially develop gross or microscopic hematuria followed by progressive nephritis which results in death in early adult life. In contrast, affected females manifest various urinary abnormalities but do not usually show deterioration in renal function and have a fairly normal life span. Nerve deafness is a common associated abnormality in some families, while ocular abnormalities, particularly cataracts and spherophakia,3 have been described in others. The ocular abnormalities affect both sexes with equal severity and may or may not be associated with renal disease in any given individual.

The present paper describes an unusual family in which three out of nine siblings two of whom are female, had chronic nephritis.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();