0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

β-Hemolytic Streptococcal Infection:  Comparison of Penicillin and Lincomycin in the Treatment of Recurrent Infections or the Carrier State

Burtis B. Breese, MD; Frank A. Disney, MD; William B. Talpey, MD; John Green, MD
Am J Dis Child. 1969;117(2):147-152. doi:10.1001/archpedi.1969.02100030149005.
Text Size: A A A
Published online

THIS study was designed to determine whether lincomycin hydrochloride monohydrate is superior to penicillin G potassium in treating recurrent streptococcal illnesses or the streptococcal carrier state or both.

In our first study on the comparative effectiveness of lincomycin and penicillin against β-hemolytic streptococci, we showed that the treatment of these infections with lincomycin resulted in fewer bacteriologic recurrences than was the case when penicillin was used. To our surprise no "carriers" of β-hemolytic streptococci occurred among 100 children treated with lincomycin whereas 12 "carriers" occurred among 102 children treated with penicillin.1 The experience of Martin F. Randolph, MD, and Raymond M. L. De Haan, MD (unpublished data) with lincomycin was similar to ours in that carriers were only infrequently found after lincomycin treatment of the initial streptococcal illness. This suggested that lincomycin might therefore be more effective than penicillin in one of the most common therapeutic problems faced by the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();