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October 1968, Vol 116, No. 4 >
Article | October 1968

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Sydney S. Gellis, MD; Murray Feingold, MD; Walter W. Tunnessen, MD; James A. Raettig, MD
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Received for publication May 10, 1968.

Reprint requests to Boston Floating Hospital, 20 Ash St, Boston 02111 (Dr. Gellis).


Am J Dis Child. 1968;116(4):407-408. doi:10.1001/archpedi.1968.02100020411011.
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Denouement and Discussion 

Caudal Dysplasia Syndrome  (Caudal Regression Syndrome)

Manifestations  The caudal regression syndrome consists of varying degrees of spinal defects and associated anomalies. It ranges from sacral agenesis which may present only with a neurogenic bladder, to the more severely affected child with complete neurological loss below the vertebral lesion.In sacral agenesis, absence of the body of the sacrum may result in a flattening of the buttocks, shortening of the intergluteal cleft, and dimpling of the buttocks. If agenesis of the lumbar spine is also present, there may be a marked disproportion between the transverse diameter of the thorax and pelvis. Incontinence of urine and feces and atrophy and diminished muscle power of the lower extremities are usually present.In the more severe cases there may be abduction and flexion deformities of the hips giving a "frog-leg" and "stuck-on" appearance and popliteal webbing. The majority of these cases

REFERENCES

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Russell, H.E., and Aitken, G.T.:  Congenital Absence of the Sacrum and Lumbar Vertebrae With Prosthetic Management , J Bone Joint Surg 45A:501-508 ( (April) ) 1963;.
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Rusnak, S., and Driscoll, S.G.:  Congenital Spinal Anomalies in Infants of Diabetic Mothers , Pediatrics 35:989-995 ( (June) ) 1965;.
3 +
Passarge, E., and Lenz, W.:  Syndrome of Caudal Regression in Infants of Diabetic Mothers: Observations of Further Cases , Pediatrics 37:672-674 ( (April) ) 1966;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Russell, H.E., and Aitken, G.T.:  Congenital Absence of the Sacrum and Lumbar Vertebrae With Prosthetic Management , J Bone Joint Surg 45A:501-508 ( (April) ) 1963;.
2 +
Rusnak, S., and Driscoll, S.G.:  Congenital Spinal Anomalies in Infants of Diabetic Mothers , Pediatrics 35:989-995 ( (June) ) 1965;.
3 +
Passarge, E., and Lenz, W.:  Syndrome of Caudal Regression in Infants of Diabetic Mothers: Observations of Further Cases , Pediatrics 37:672-674 ( (April) ) 1966;.

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