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Karyotyp und Phänotyp der Autosomalen Chromosomenaberrationen Beim Menschen

EBERHARD PASSARGE, MD
Am J Dis Child. 1968;116(2):224. doi:10.1001/archpedi.1968.02100020226021.
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ABSTRACT

This monograph summarizes much of the total clinical experience of the first six years of modern cytogenetics, with special reference to karyotype-phenotypic relations of autosomal aberrations. The book, resulting from the author's Habilitationsschrift in Münster, is intended for the specialist, as the great many clinical and cytological details presented would make the book indigestible for the casual reader.

Following a brief summary in English, the text is presented in the following three parts: (1) the karyotype (53 pages); (2) the phenotype (170 pages); and (3) conclusions about the relation of chromosomal aberrations and phenotypic manifestations (26 pages).

Both the strength and the weakness of this work are its considerable length and the richness of detail, not all essential, but often interesting to clinically oriented cytogeneticists. All autosomal aberrations known through 1965 are described or referred to. The material is arranged according to cytogenetic criteria. The text is well illustrated, and

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