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Central Nervous System Disease in a Newborn Infant

Harry T. Wright Jr., MD; George Reed, MD; Benjamin H. Landing, MD
Am J Dis Child. 1968;115(6):739-745. doi:10.1001/archpedi.1968.02100010741019.
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THE POSSIBLE etiology of central nervous system (CNS) disease in a newborn infant is discussed by three physicians. A representative case is presented. This communication is the result of a clinical conference at the Childrens Hospital of Los Angeles.

Report of a Case  History.—A 10-day-old boy was admitted to the Childrens Hospital of Los Angeles because of a loss of appetite. The infant weighed 2,666 gm (5 lb 14 oz) at birth and was delivered without complications. Tenacious mucus was noted in his oropharynx at birth. The baby was a "poor feeder" and gavage feedings with modified milk food (Similac) were instituted. At 3 days of age he was jaundiced with a total serum bilirubin of 9.3 mg/100 cc. At 1 week of age, the infant weighed 2,467 gm (5 lb 7 oz); he was discharged from the hospital at the insistence of the parents. At home the infant


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