DOWN'S SYNDROME has been found in all major races,1-11 but there are few quantitative studies of clinical signs on groups other than whites. The occurrence of major malformations in Down's syndrome has been reviewed recently by Warkany, et al.12 A previous report qualitatively discussed the physical findings in a series of 20 Chinese children with Down's syndrome,9 and some quantitative data are available for a series of 11 Japanese cases.5 Quantitative data are available for 29 cases of Oriental origin (Chinese, Japanese, and other) in Hawaii.4
The present article is a study of the frequency of previously described stigmata in a sample of 56 Chinese children with Down's syndrome born in the area of Taipei, Taiwan. It is one phase of a comprehensive investigation of Down's syndrome in Chinese. The other phases, including cytogenetics, dermatoglyphics, and epidemiology, will be reported elsewhere.
Report of Cases