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Physical Features of Chinese Children With Down's Syndrome

Irvin Emanuel, MD; Shih-Wen Huang, MD; Eng-Kung Yeh, MD
Am J Dis Child. 1968;115(4):461-468. doi:10.1001/archpedi.1968.02100010463009.
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DOWN'S SYNDROME has been found in all major races,1-11 but there are few quantitative studies of clinical signs on groups other than whites. The occurrence of major malformations in Down's syndrome has been reviewed recently by Warkany, et al.12 A previous report qualitatively discussed the physical findings in a series of 20 Chinese children with Down's syndrome,9 and some quantitative data are available for a series of 11 Japanese cases.5 Quantitative data are available for 29 cases of Oriental origin (Chinese, Japanese, and other) in Hawaii.4

The present article is a study of the frequency of previously described stigmata in a sample of 56 Chinese children with Down's syndrome born in the area of Taipei, Taiwan. It is one phase of a comprehensive investigation of Down's syndrome in Chinese. The other phases, including cytogenetics, dermatoglyphics, and epidemiology, will be reported elsewhere.

Report of Cases  Physical


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