April 1968, Vol 115, No. 4 >

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Article | April 1968

Physical Features of Chinese Children With Down's Syndrome

Irvin Emanuel, MD; Shih-Wen Huang, MD; Eng-Kung Yeh, MD

Am J Dis Child. 1968;115(4):461-468. doi:10.1001/archpedi.1968.02100010463009.

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DOWN'S SYNDROME has been found in all major races,^1-11 but there are few quantitative studies of clinical signs on groups other than whites. The occurrence of major malformations in Down's syndrome has been reviewed recently by Warkany, et al.¹² A previous report qualitatively discussed the physical findings in a series of 20 Chinese children with Down's syndrome,⁹ and some quantitative data are available for a series of 11 Japanese cases.⁵ Quantitative data are available for 29 cases of Oriental origin (Chinese, Japanese, and other) in Hawaii.⁴

The present article is a study of the frequency of previously described stigmata in a sample of 56 Chinese children with Down's syndrome born in the area of Taipei, Taiwan. It is one phase of a comprehensive investigation of Down's syndrome in Chinese. The other phases, including cytogenetics, dermatoglyphics, and epidemiology, will be reported elsewhere.

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Emanuel I, Huang S, Yeh E. Physical Features of Chinese Children With Down's Syndrome. Am J Dis Child. 1968;115(4):461-468. doi:10.1001/archpedi.1968.02100010463009.

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