Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Thrombocytopenic Purpura Following Vaccination With Attenuated Measles Virus

H. J. Alter, MD; R. T. Scanlon, MD; Geraldine P. Schechter, MD
Am J Dis Child. 1968;115(1):111-113. doi:10.1001/archpedi.1968.02100010113022.
Text Size: A A A
Published online


HEMORRHAGIC PHENOMENA constitute a rare complication of measles infection. Hudson et al1 in their review of the literature, were able to cite only 22 well-documented cases, all of which were secondary to thrombocytopenia. In 1966, Oski and Naiman2 reported the thrombocytopenic effect of live attenuated measles virus vaccine. They demonstrated a significant though generally mild depression of platelets in a large proportion of children receiving this vaccine. However, total platelet count never fell below 64,000, and in no instance were purpuric manifestations noted. We believe the patient reported herein to represent the first recognized case of thrombocytopenic purpura secondary to measles vaccination.

Report of a Case  The patient was a 14-month-old white boy at the onset of thrombocytopenic purpura. He had been delivered by cesarean section at 35 weeks of fetal life, surgery being necessitated by placenta previa. His birth weight was 2,098 gm (4 lb 10 ounces)


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.