To the Editor.—Dr. Passarge's statements and suggestions are entirely sound—a newborn infant with generalized petechial rash and bilaterally absent radii is much more likely to have the hemimelia-thrombocytopenia syndrome than Fanconi's anemia. In the latter, hematological disorders tend to appear later. However in the case published, the diagnosis of Fanconi's anemia rested on the presence of pancytopenia which is not present in the hemimelia-thrombocytopenia syndrome. In addition, the infant died at 4 months of age and the diagnosis of Fanconi's anemia was confirmed at autopsy.