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Cardiac Output by Fick Principle in Infants and Young Children

Martin H. Lees, MD; J. David Bristow, MD; Clifton Way, MD; Mary Brown
Am J Dis Child. 1967;114(2):144-149. doi:10.1001/archpedi.1967.02090230074006.
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A VARIETY OF methods is available for the measurement of cardiac output in the older child; but in the young child and infant considerations of blood volume and lack of cooperation of the subject make the classical techniques difficult.

We wish to report briefly our experiences with the measurement of oxygen consumption by a "flow-through" method and the measurement of oxygen saturation by reflection oximetry. Use of these two techniques allows the calculation of blood flows by the Fick principle (cardiac output = oxygen consumption ÷ arteriovenous oxygen content difference). We report here a statistical evaluation of the reliability of both "flow-through" oxygen consumption measurement and reflection oximetry, and, comment on our experiences with these techniques during the hemodynamic study of 150 infants and children.

Methods  "Flow-Through" Measurement of Oxygen Consumption.—The continuous "flow-through" oxygen and carbon dioxide gas analyzer was used for determination of oxygen consumption (O2). With this


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