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A Comparison of the Efficacy of Emetic Drugs and Stomach Lavage FREE

A. H. Abdallah, MSc; A. Tye, PhD
[+] Author Affiliations

Received for publication June 3, 1966.

Read in part before the American Association of Poison Control Centers, sixth annual meeting, Oct 6, 1963, Chicago.

Reprint requests to 1958 Neil Ave, Columbus, Ohio 43210 (Dr. Tye).


Am J Dis Child. 1967;113(5):571-575. doi:10.1001/archpedi.1967.02090200103010.
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ACCORDING TO Arena,1 and Krimmel and Sunshine,2 more than 500,000 cases of poisoning occur each year in this country, with about 1,500 resultant deaths. Arena1 states that the number of child deaths from accidental poisoning exceeds the total number of deaths caused by measles, polio, scarlet fever, and diphtheria.

In many types of poisoning the primary step in treatment is to evacuate the stomach. Berry and Lambdin3 point out that one of two methods is generally employed for emptying the stomach of toxic material; stomach lavage or pharmacologically-induced emesis. There are differences of opinion as to which is the best method: Robertson4 suggested the use of syrup of ipecac, Berry and Lambdin3 prefer apomorphine hydrochloride (HCl), while Arnold et al5 found that stomach lavage is less effective than syrup of ipecac.

Since there seems to be no general agreement as to which is

REFERENCES

Arena, J.M.:  Poisoning in Childhood , Clin Pediat 2:1, 1963;.
Krimmel, H.E., and Sunshine, I.:  Poison in Your Home: Beware , PTA Magazine 55:17, 1961;.
Berry, F.A., and Lambdin, M.A.:  Apomorphine and Levallorphan Tartrate in Acute Poisoning , Amer J Dis Child 105:160, 1963;.
Robertson, W.O.:  Syrup of Ipecac: A Slow or Fast Emetic , Amer J Dis Child 103:136, 1962;.
Arnold, F.J., Jr., et al:  Evaluation of the Efficacy of Lavage and Induced Emesis in Treatment of Salicylate Poisoning , Pediatrics 23:286, 1959;.
Pharmacopeia of the United States, revision 17, 1960, p 76.
Frediani, H.A., and Bablee, B.J.:  Colorimetric Method of Determination of Barium , Analyst 64:915, 1939;.
Ng, K.K.:  A New Pharmacological Action of Emetine , Brit Med J 1:1278, 1966;.
Dutoit, C.H., and Christenson, W.R.: Environment Protection Series, Report No. 216, Office of The Quartermaster General, Department of the Army, 1962, p 169.
Bates, T., and Grunwaldt, E.:  Ipecac Poisoning , Amer J Dis Child 103:169, 1962;.
Allport, R.B.:  Ipecac Is Not Innocuous , Amer J Dis Child 98:786, 1959;.
Matthew, H., et al:  Gastric Aspiration and Lavage in Acute Poisoning , Brit Med J 1:1333, 1966;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Arena, J.M.:  Poisoning in Childhood , Clin Pediat 2:1, 1963;.
Krimmel, H.E., and Sunshine, I.:  Poison in Your Home: Beware , PTA Magazine 55:17, 1961;.
Berry, F.A., and Lambdin, M.A.:  Apomorphine and Levallorphan Tartrate in Acute Poisoning , Amer J Dis Child 105:160, 1963;.
Robertson, W.O.:  Syrup of Ipecac: A Slow or Fast Emetic , Amer J Dis Child 103:136, 1962;.
Arnold, F.J., Jr., et al:  Evaluation of the Efficacy of Lavage and Induced Emesis in Treatment of Salicylate Poisoning , Pediatrics 23:286, 1959;.
Pharmacopeia of the United States, revision 17, 1960, p 76.
Frediani, H.A., and Bablee, B.J.:  Colorimetric Method of Determination of Barium , Analyst 64:915, 1939;.
Ng, K.K.:  A New Pharmacological Action of Emetine , Brit Med J 1:1278, 1966;.
Dutoit, C.H., and Christenson, W.R.: Environment Protection Series, Report No. 216, Office of The Quartermaster General, Department of the Army, 1962, p 169.
Bates, T., and Grunwaldt, E.:  Ipecac Poisoning , Amer J Dis Child 103:169, 1962;.
Allport, R.B.:  Ipecac Is Not Innocuous , Amer J Dis Child 98:786, 1959;.
Matthew, H., et al:  Gastric Aspiration and Lavage in Acute Poisoning , Brit Med J 1:1333, 1966;.

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