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Rubella Retinitis

Beatrice Kresky, MD; Jack S. Nauheim, MD
Am J Dis Child. 1967;113(3):305-310. doi:10.1001/archpedi.1967.02090180065003.
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THE OCCURRENCE of retinopathy in infants and children whose mothers had rubella in the first trimester of pregnancy was originally documented by Gregg in 1942 and Swan in 1943.1,2 While the entity of rubella retinopathy has been well described in the ophthalmologic literature, pediatricians are not generally aware of its existence. The disease consists of a pigment disturbance most often involving the posterior pole of the eye and most marked in the macula region. It may occur in one or both eyes and has been variously described as consisting of small, black, irregular masses varying in size,3 fine to gross pigmentary stippling with colloid changes and waxy disc,4 coarse mottling of the macula,1 and measly or blotchy changes.1 Morlet classifies three types of fundus changes: gross and generalized pigmentary changes; pepper-like pigmentary changes which are mainly peripheral; and strange, moth-eaten areas, some diffuse, others occurring


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