Pulmonary Hemorrhage in the Newborn FREE

A. James McAdams, MD

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Received for publication Aug 5, 1966.

Reprint requests to Elland Ave and Bethesda, Cincinnati 45229 (Dr. McAdams).

Am J Dis Child. 1967;113(2):255-262. doi:10.1001/archpedi.1967.02090170119014.

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ABSTRACT

ABSTRACT | REFERENCES

A RELATIVELY neglected factor, which in the newly born may be responsible for adverse pulmonary symptoms, has been pulmonary hemorrhage. Although well recognized, at least as an autopsy finding, the systematic studies of Ahvenainen^1,2 have stood until very recently as the only significant contributions to the subject.^3,4 Much remains to be understood about pulmonary hemorrhage, if only to define its interrelationships. The purpose of this paper is to demonstrate and to explain, when possible, meaningful relationships between significant pulmonary hemorrhage and other findings in the neonatal autopsy.

Material and Methods The autopsies of all infants who had died within the first two weeks of life at the Cincinnati Children's Hospital were reviewed, yielding records of 322 infants which could be satisfactorily evaluated. An additional 22 infants were excluded either because permission had not been granted for examination of the brain, or because the available material was inadequate. The

REFERENCES

ABSTRACT | REFERENCES

Ahvenainen, E.K., and Call, J.D.: Pulmonary Hemorrhage in Infants , Amer J Path 28:1-18, 1952;.

Ahvenainen, E.K.: Massive Pulmonary Hemorrhage in Newborn , Ann Paediat Fenn 2:44-55, 1956;.

Esterly, J.R., and Oppenheimer, E.H.: Massive Pulmonary Hemorrhage in the Newborn: I. Pathologic Considerations , J Pediat 69:3-11, 1966;.

Rowe, S., and Avery, M.E.: Massive Pulmonary Hemorrhage in the Newborn: II. Clinical Considerations , J Pediat 69:12-20, 1966;.

Scholz, N.: Selective Neuronal Necrosis and Its Topistic Patterns in Hypoxemia and Oligemia , J Neuropath 12:249-261, 1953;.

Perrin, E.V., and Landing, B.H.: Schmorl Lesion of Jaundiced Infected Infants , abstracted, Amer J Dis Child , 104:551, 1962;.

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Driscoll, S.G., and Smith, C.A.: Neonatal Pulmonary Disorders , Pediat Clin N Amer 9:325-352, 1962;

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Landing, B.H.: Pathologic Features of Respiratory Distress Syndromes in Newborn Infants , Amer J Roentgen 74:796-799, 1955;.

Sarnoff, S.J., and Berghand, E.: Neurohemodynamics of Pulmonary Edema: IV. Effect of Systemic Vasoconstriction and Subsequent Vasodilatation on Flow and Pressures in Systemic and Pulmonary Vascular Beds , Amer J Physiol 170:588-600, 1952;.

Luisada, A.A., and Cardi, L.: Acute Pulmonary Edema , Circulation 13:113-135, 1956;.

Campbell, G.S.: Circulatory Change and Pulmonary Lesions in Dogs Following Increased Intracranial Pressure, and the Effects of Atropine Upon Such Changes , Amer J Physiol 158:96-102, 1949;.

Richards, P.: Pulmonary Oedema and Intracranial Lesions , Brit Med J 2:83-89, 1963;.

Aherne, W.: " Neonatal Pulmonary Disease ," in S.C. Dyke: Recent Advances in Clinical Pathology , Series IV, Boston: Little, Brown and Co., 1964;, pp 284-305.

Mann, T.P., and Elliott, R.I.: Neonatal Cold Injury Due to Accidental Exposure to Cold , Lancet 1:229-234, 1957;.

Bower, B.D.; Jones, L.F.; and Weeks, M.M.: Cold Injury in the Newborn: A Study of 70 Cases , Brit Med J 1:303-309, 1960;.

Zuelzer, W.W., and Madgett, R.T.: Kernicterus , Pediatrics 6:452-474, 1950;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal