CLINICAL HISTORY.—This 13-hour-old girl was admitted to the Los Angeles Children's Hospital shortly after birth because of purpuric skin lesions. The infant's mother's delivery was uneventful and followed a 10-hour labor.
During the gestation period, the mother had several episodes of poison oak dermatitis. In the second month of pregnancy, she developed a rash on the chest, abdomen, and buttocks and was told this was an exacerbation of the dermatitis. The family history was otherwise noncontributory.
Multiple purpuric and petechial skin lesions were noted upon physical examination of the infant. The eyes were normal and no cardiac nurmur was detected. The abdomen was protuberant and hepatosplenomegaly was present. The remainder of the physical examination was within normal limits.
The hemoglobin was 22.2 gm/100 ml; white blood cells, 12,600/cu mm, with a normal differential; and platelets, 18,000/cu mm. A bleeding time of two minutes and a clotting time of four minutes