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Congenital Scalp Defects in Father and Son

Am J Dis Child. 1965;110(3):297-298. doi:10.1001/archpedi.1965.02090030311014.
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FAMILIAL OCCURRENCE of congenital scalp defects was reported by William Campbell in 1826. He described two cases of aplasia cutis congenita of the scalp.1 Many subsequent examples of familial congenital scalp defects have been recorded.1-7 A family in which both the father and the son had scalp defects is reported here.

Report of a Case  The propositus was the third born child of a 35-year-old mother and a 40-year-old father. The infant was delivered from a vertex presentation at 42 weeks gestation and weighed 11 lb 2 oz (5,040 gm) at birth. At delivery, the child had two small (1.5 cm in diameter) punched-out defects of the scalp (Fig 1). The borders were well demarcated and the bases were depressed and slightly roughened. No other abnormalities were found. Roentgenograms of the skull showed areas of thinned calvaria under the skin defects. No lytic lesion was apparent. The child


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