To the Editor: I was interested to read the case report "Hand-Foot Syndrome Due to Streptococcal Infection" by Drs. Haltalin and Nelson (AMER J Dis CHILD 109:156 [Feb] 1965). This condition is indeed very rare. I have reported an almost similar case in a baby of 10 months of age who had fever and swelling of both hands and feet. On the 16th day of illness, the radiological examination revealed extensive bilateral involvement of small bones of the hands and feet. The blood culture was sterile, but unfortunately, some penicillin had been administered before the blood sample was cultured. The child made a complete recovery with tetracycline and continues to grow normally.