To the Editor: The conclusion of Snyderman and Holt that "subjects 4 and 5 show an inferior growth performance" is based on their own somewhat misleading weight charts. The enclosed figure (Fig 2), plotted on the basis of weights at the actual ages when change in feeding occurred, demonstrates that weight gain was normal during periods when formula S3* was fed. This method of presentation is, however, less satisfactory than that employed in the original publication. Why Snyderman and Holt choose to ignore Fig 1 of the original publication is not clear.
Snyderman and Holt have come to the remarkable conclusion that nitrogen retention is satisfactory only when enough nitrogen is retained to account for 2.5% of weight gained. According to this criterion, nitrogen retention by the normal breast-fed infant would be considered inadequate during the first two or three months of life. Our reasons for rejecting the hypothesis that