WHILE studying serum immune globulin concentrations in a group of allergic children,1 one patient with markedly elevated serum γ1A-globulins was found. This boy had severe asthma, growth retardation, allergic rhinitis, and a history of eczema and recurrent urticaria. His case history is presented below.
Report of a Case
Personal History.—The patient, a 14-year-old white male, was first seen by us in September of 1962 at the age of 123/12 years with the chief complaint of asthma.His first episode of wheezing occurred at 3 months of age and asthmatic symptoms were perennial and severe from that time on. Eczema appeared at the same time, was generalized, and persisted until age 2½ years. Symptoms of allergic rhinitis appeared during the first year of life and recurrent urticaria and angioneurotic edema related to foods (beans and eggs) were troublesome. There was a history of pulmonary and ear infections