To the Editor: The paper by Farrehi et al Amer J Dis Child 108:335, 1964) on "Supravalvular Aortic Stenosis" emphasizes the rarity of the cardiovascular anomaly when it is associated with a peculiar facies and mental retardation. That the syndrome is relatively common was attested to by a show of hands at Dr. Helen Taussig's 1964 Cardiac Clinic Reunion demonstrating a large number of cases from a widespread geographic distribution.
Farrehi and his associates incorrectly stated that no cases have been recognized before 5 years of age.1 I should like to emphasize that an association with idiopathic hypercalcemia is most likely to be missed unless the syndrome is diagnosed in infancy. Moreover, unless early diagnosis is made there is no possibility of arresting whatever process it is that leads to the mental retardation of this group of cases. The infant already reported1 has shown definite improvement in psychomotor development