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Human Foetal and Neonatal Circulation.

Am J Dis Child. 1964;108(6):700. doi:10.1001/archpedi.1964.02090010702022.
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This short, profusely illustrated monograph summarizes present knowledge relating to the physiology of circulation from immediately before birth through the first several days afterward by following the successive steps in transition from fetal to newborn states. The authors, through their previous research, have been in large part responsible for showing that failure of the circulatory system to make the normal transition underlies much of the hypoxia and asphyxia which in turn are major causes of mortality and morbidity in the neonatal period. A number of years ago, Sir Joseph Barcroft and his associates after their excellent studies on circulation in fetal and newborn lambs suggested that similar studies should be carried out on human fetuses as soon as suitably refined techniques could be devised. The authors not only helped devise the techniques but took the lead in judiciously applying them to the human fetal material available to them in Sweden.


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