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REGARDING MANUSCRIPT BY DR. KOLLBERG FREE

PHILIP SUNSHINE, MD
Am J Dis Child. 1964;107(5):536-537. doi:10.1001/archpedi.1964.02080060538019.
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To the Editor: We thank Dr. Kollberg for his pertinent comments. When Dr. Yaffe and I initially saw this patient our concern was that she was indeed hyponatremic secondary to electrolyte changes induced by the lavaging with distilled water. We measured the wash water which had been returned, and we could account for the 2,000 ml of the fluid used in the lavage. Unfortunately, this fluid was inadvertently discarded and we could not measure the amount of amitriptyline which had been removed.

A serum sodium drawn at that time (three hours after the patient ingested the drug) was 140 mEq/liter and not 132 mEq/liter as stated by Dr. Kollberg. (Table 1 of the original article.) Since the patient had received no electrolyte-containing solutions until the time the serum sodium was measured, we could not attribute the patient's symptoms to hyponatremia.

In view of these data, we disagree with Dr. Kollberg's

REFERENCES

Fendrick, G. M.:  Amitriptyline Poisoning , New Eng J Med 267:1031, 1962;.
Sharp, W. L.:  Convulsions Associated With Anti-Depressant Drugs , Amer J Psychiat 117:458, 1960;.
Mann, A. M.; Catterson, A. G.; and MacPherson, A. S.:  Toxicity of Imipramine: Report of Serious Side Effects and Massive Overdosage , Canad Med Ass J 81:23, 1959;.
Alajem, N., and Albagli, C.:  Severe Imipramine Poisoning in Infant , Amer J Dis Child 103:702, 1962;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Fendrick, G. M.:  Amitriptyline Poisoning , New Eng J Med 267:1031, 1962;.
Sharp, W. L.:  Convulsions Associated With Anti-Depressant Drugs , Amer J Psychiat 117:458, 1960;.
Mann, A. M.; Catterson, A. G.; and MacPherson, A. S.:  Toxicity of Imipramine: Report of Serious Side Effects and Massive Overdosage , Canad Med Ass J 81:23, 1959;.
Alajem, N., and Albagli, C.:  Severe Imipramine Poisoning in Infant , Amer J Dis Child 103:702, 1962;.

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