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TESTICULAR HILAR NODES IN ADRENOGENITAL SYNDROME

FRED A. BAUGHMAN JR., MD
Am J Dis Child. 1964;107(3):316. doi:10.1001/archpedi.1964.02080060318018.
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To the Editor: Testicular hilar nodules (Shanklin, D. R.; Richardson, A. P., Jr., and Rothstein, G.: Amer J Dis Child 106:243, 1963.) are not peculiar to the adrenogenital syndrome. Such cell aggregates have been encountered in the 'streak' gonads of patients with Turner's syndrome with superadded features of masculinization.

Del Castillo, et al1 (1947) described an 18-year-old female with retarded growth, eunuchoid proportions, cubitus valgus, primary amenorrhea, infantile mammae, internal and external genitalia, hirsutism, and elevated 17-ketosteroids. Laparotomy revealed white cords of one-half cm diameter in place of the ovaries. No differentiated ovarian elements were seen but a small conglomerate of cells was noted, "possibly an inclusion of aberrant cells of the adrenal cortex."

Gordan et al2 described two such cases under the title: "A Syndrome of Gonadal Dysgenesis: A Variety of Ovarian Agenesis With Androgenic Manifestations." A sex chromatin count, performed only on the first of these

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