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An Epidemic of Erythema Infectiosum FREE

PETER GREENWALD, MD; WINSLOW J. BASHE, MD
[+] Author Affiliations

Received for publication Aug 9, 1963.

Epidemiology Intelligence Service Officer from the Communicable Disease Center, United States Public Health Service, Atlanta, Ga, assigned to the Division of Communicable Diseases, Ohio Department of Health, Columbus (Dr. Greenwald); Chief of the Division of Communicable Diseases, Ohio Department of Health, Columbus, at the time of this study, at present Associate Professor of Preventive Medicine, University of Cincinnati College of Medicine (Dr. Bashe).


Am J Dis Child. 1964;107(1):30-34. doi:10.1001/archpedi.1964.02080060032005.
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Erythema infectiosum, or "The Fifth Disease," is a poorly understood illness which can easily be recognized in epidemics. In nonepidemic situations recognition is possible but more difficult, frequently resulting in unnecessary treatment, extended absence from school, and undue concern on the part of both the physician and parent. This paper is presented as a reminder that this disease does exist as well as to define some of its epidemiologic characteristics.

Methods  In January, 1963 (following the Christmas holidays), small outbreaks of a mild exanthematous illness were reported from several areas of the country. An outbreak of illness with the same characteristics developed among many children of an elementary school in Circleville, Ohio. Histories and physical examinations performed by us on 38 affected children elicited symptoms and signs compatible with erythema infectiosum. A questionnaire sent to parents of all students attending the school provided information for 286 households, with a

REFERENCES

Condon, F. J.:  Erythema Infectiosum: Report of an Area-Wide Outbreak , Amer J Public Health 49:528, 1959;.
Lawton, A. L., and Smith, R. E.:  Erythema Infectiosum: Clinical Study of Epidemic in Branford, Conn ., Arch Intern Med 47:28, 1931;.
Chargin, L.; Sobel, N.; and Goldstein, H.:  Erythema Infectiosum: Report of Extensive Epidemic , Arch Derm Syph 47:467, 1943;.
Fox, M. J., and Clark, J. M.:  Erythema Infectiosum , Amer J Dis Child 73:453, 1947;.
Kerr, P. S., and Marsh, E. H.:  Outbreak of Erythema Infectiosum in Elmsford, NY , Amer J Public Health 23:1271, 1933;.
Coe, H. C., and Kelly, F. L.:  Erythema Infectiosum , Calif Western Med 36:39, 1932;.
Zukermann, S. N.:  Erythema Infectiosum, With Report of Epidemic in San Francisco , Arch Pediat 57:168, 1940;.
Freeble, C. R., Jr., and Pearse, A. J.:  Ery-Erythema Infectiosum , Public Health Rep 66:1220, 1951;.
Tschamer, A.:  Über örtliche Rötheln , Jahrb Kinderheilk 29:372, 1889;.
Shaw, H. L. K.:  Erythema Infectiosum , Amer J Med Sci 129:16, 1905;.
Shaw, H. L. K.: " Erythema Infectiosum ," in Pediatrics , edited by I. A. Abt, Philadelphia: W. B. Saunders Company, 1924;, vol 5, p 660.
Zahorsky, J.:  An Epidemic of Erythema Infectiosum , Amer J Dis Child 28:261, 1924;.
Herrick, T. P.:  Erythema Infectiosum: A Clinical Report of 74 Cases , Amer J Dis Child 31: 486, 1926;.
Smith, E. H.:  Epidemic of Erythema Infectiosum: The Fifth Disease , Arch Pediat 46: 456, 1929;.
Phillips, I. E.:  Erythema Infectiosum: Outbreak in Bristol Tennessee-Virginia Area , AMA Arch Derm Syph 67:628, 1953;.
Phillips, I. E.:  Erythema Infectiosum: Clinical and Epidemiological Observations , Southern Med J 47:253, 1954;.
Kobayashi, C. K., and Moore, W. F.: " Erythema Infectiosum ," in Brennemann's Practice of Pediatrics , edited by I. H. McQuarrie, Hagerstown, Md: W. F. Prior Co., 1960;, vol 2, p 9.
Sprunt, K.:  Newly Isolated Viruses as Causes of Disease , Amer J Med Sci 233:688, 1957;.
Werner, G. H.; Brachman, P. S.; Ketler, A.; Scully, J.; and Rake, J.:  The Fifth Disease: An Epidemic of Acute Exanthem in Reading, Pa., 1955 , Ann NY Acad Sci 67:388, 1957;.

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References

Condon, F. J.:  Erythema Infectiosum: Report of an Area-Wide Outbreak , Amer J Public Health 49:528, 1959;.
Lawton, A. L., and Smith, R. E.:  Erythema Infectiosum: Clinical Study of Epidemic in Branford, Conn ., Arch Intern Med 47:28, 1931;.
Chargin, L.; Sobel, N.; and Goldstein, H.:  Erythema Infectiosum: Report of Extensive Epidemic , Arch Derm Syph 47:467, 1943;.
Fox, M. J., and Clark, J. M.:  Erythema Infectiosum , Amer J Dis Child 73:453, 1947;.
Kerr, P. S., and Marsh, E. H.:  Outbreak of Erythema Infectiosum in Elmsford, NY , Amer J Public Health 23:1271, 1933;.
Coe, H. C., and Kelly, F. L.:  Erythema Infectiosum , Calif Western Med 36:39, 1932;.
Zukermann, S. N.:  Erythema Infectiosum, With Report of Epidemic in San Francisco , Arch Pediat 57:168, 1940;.
Freeble, C. R., Jr., and Pearse, A. J.:  Ery-Erythema Infectiosum , Public Health Rep 66:1220, 1951;.
Tschamer, A.:  Über örtliche Rötheln , Jahrb Kinderheilk 29:372, 1889;.
Shaw, H. L. K.:  Erythema Infectiosum , Amer J Med Sci 129:16, 1905;.
Shaw, H. L. K.: " Erythema Infectiosum ," in Pediatrics , edited by I. A. Abt, Philadelphia: W. B. Saunders Company, 1924;, vol 5, p 660.
Zahorsky, J.:  An Epidemic of Erythema Infectiosum , Amer J Dis Child 28:261, 1924;.
Herrick, T. P.:  Erythema Infectiosum: A Clinical Report of 74 Cases , Amer J Dis Child 31: 486, 1926;.
Smith, E. H.:  Epidemic of Erythema Infectiosum: The Fifth Disease , Arch Pediat 46: 456, 1929;.
Phillips, I. E.:  Erythema Infectiosum: Outbreak in Bristol Tennessee-Virginia Area , AMA Arch Derm Syph 67:628, 1953;.
Phillips, I. E.:  Erythema Infectiosum: Clinical and Epidemiological Observations , Southern Med J 47:253, 1954;.
Kobayashi, C. K., and Moore, W. F.: " Erythema Infectiosum ," in Brennemann's Practice of Pediatrics , edited by I. H. McQuarrie, Hagerstown, Md: W. F. Prior Co., 1960;, vol 2, p 9.
Sprunt, K.:  Newly Isolated Viruses as Causes of Disease , Amer J Med Sci 233:688, 1957;.
Werner, G. H.; Brachman, P. S.; Ketler, A.; Scully, J.; and Rake, J.:  The Fifth Disease: An Epidemic of Acute Exanthem in Reading, Pa., 1955 , Ann NY Acad Sci 67:388, 1957;.

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