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August 1963, Vol 106, No. 2 >
Article | August 1963

Transplacental Infection by Herpes Simplex Virus FREE

JOE E. MITCHELL, MD; FRED C. McCALL, MD
[+] Author Affiliations

Submitted for publication Jan 23, 1963.


Am J Dis Child. 1963;106(2):207-209. doi:10.1001/archpedi.1963.02080050209015.
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One of the more common viral infections affecting man is that caused by the herpes simplex virus. Its most common manifestation, the "fever blister," is so familiar to the layman that a medical diagnosis is not sought. However, the manifestations of the herpes virus are so protean that they may range from severe encephalitis, to the moderately severe stomatitis frequently seen in the very young, to the mild "fever blister" just mentioned. The more severe manifestations are due to a primary infection which occurs after an incubation period of three to five days, whereas the "fever blister" is felt to be the result of an upset in an otherwise symbiotic relationship between host and virus. Between 65% and 98% of adults, depending on areas sampled, will show neutralizing antibodies to the herpes simplex virus.

Since the initial case report of herpes simplex infection in the newborn by Haas 1 in

REFERENCES

1 +
Haas, G. M.:  Hepato-Adrenal Necrosis With Intranuclear Inclusion Bodies , Amer J Path 11:127, 1935;.
2 +
Zuelzer, W. W., and Stulberg, C. G.:  Herpes Simplex Virus as the Cause of Fulminating Visceral Disease and Hepatitis in Infancy , AMA Amer J Dis Child 83:421, 1952;.
3 +
Florman, A. L., and Mindlin, R. L.:  Generalized Herpes Simplex in an 11-Day-Old Premature Infant , AMA Amer J Dis Child 83:481, 1952;.
4 +
Bird, T., and Gardner, P. S.:  Disseminated Herpes Simplex in the Newborn , Brit Med J 2:993, 1959;.
5 +
Williams, A., and Jack, I.:  Hepatic Necrosis in Neonatal Herpes Simplex Infection , Med J Aust 1:392, 1955;.
6 +
Jack, I., and Perry, J. W.:  Herpes Simplex Infection in the New-Born , Med J Aust 46:640, 1959;.
7 +
Mozziconacci, P.:  L'Herpes du nouveau , Rev Prat (Paris) 11:2323, 1961;.
8 +
Alison, F., and Lelong, M.:  La maladie herpetique du nouveau , Arch Franc Pediat 12:3, 1955;.
9 +
Lamy, M. O.; Jammett, J. L.; Granjon, A.; Veslot, J.; Daniel, P.; Nezelof, C.; and Cottin, S.:  L'Herpes du nouveau-ne , Arch Franc Pediat 17:425, 1960;.
10 +
McDougal, R. A.; Beamer, P. R.; and Hellerstein, S.:  Fatal Herpes Simplex Hepatitis in a Newborn Infant , Amer J Clin Path 24:1250, 1954;.
11 +
Epstein, H. C., and Crouch, W. L.:  Herpes Simplex of the Newborn Infant , Pediatrics 13:553, 1954;.
12 +
Johnson, W. W.: Fatal Herpes Simplex in the Newborn: Report of Three Cases, reported at Tennessee Pathological Meeting, March, 1962.
13 +
Schaffer, A. J.: Diseases of the Newborn , Philadelphia: W. B. Saunders Company, 1960;, p 662.
14 +
Wheeler, C. E. (University of North Carolina, School of Medicine): Personal communication to the authors.
15 +
Sabin, A. B., and Feldman, H. A.:  Chorioretinopathy Associated With Other Evidence of Cerebral Damage in Childhood: A Syndrome of Unknown Origin Separable From Congenital Toxoplasmosis , Amer J Dis Child 79:366-368, 1950;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Haas, G. M.:  Hepato-Adrenal Necrosis With Intranuclear Inclusion Bodies , Amer J Path 11:127, 1935;.
2 +
Zuelzer, W. W., and Stulberg, C. G.:  Herpes Simplex Virus as the Cause of Fulminating Visceral Disease and Hepatitis in Infancy , AMA Amer J Dis Child 83:421, 1952;.
3 +
Florman, A. L., and Mindlin, R. L.:  Generalized Herpes Simplex in an 11-Day-Old Premature Infant , AMA Amer J Dis Child 83:481, 1952;.
4 +
Bird, T., and Gardner, P. S.:  Disseminated Herpes Simplex in the Newborn , Brit Med J 2:993, 1959;.
5 +
Williams, A., and Jack, I.:  Hepatic Necrosis in Neonatal Herpes Simplex Infection , Med J Aust 1:392, 1955;.
6 +
Jack, I., and Perry, J. W.:  Herpes Simplex Infection in the New-Born , Med J Aust 46:640, 1959;.
7 +
Mozziconacci, P.:  L'Herpes du nouveau , Rev Prat (Paris) 11:2323, 1961;.
8 +
Alison, F., and Lelong, M.:  La maladie herpetique du nouveau , Arch Franc Pediat 12:3, 1955;.
9 +
Lamy, M. O.; Jammett, J. L.; Granjon, A.; Veslot, J.; Daniel, P.; Nezelof, C.; and Cottin, S.:  L'Herpes du nouveau-ne , Arch Franc Pediat 17:425, 1960;.
10 +
McDougal, R. A.; Beamer, P. R.; and Hellerstein, S.:  Fatal Herpes Simplex Hepatitis in a Newborn Infant , Amer J Clin Path 24:1250, 1954;.
11 +
Epstein, H. C., and Crouch, W. L.:  Herpes Simplex of the Newborn Infant , Pediatrics 13:553, 1954;.
12 +
Johnson, W. W.: Fatal Herpes Simplex in the Newborn: Report of Three Cases, reported at Tennessee Pathological Meeting, March, 1962.
13 +
Schaffer, A. J.: Diseases of the Newborn , Philadelphia: W. B. Saunders Company, 1960;, p 662.
14 +
Wheeler, C. E. (University of North Carolina, School of Medicine): Personal communication to the authors.
15 +
Sabin, A. B., and Feldman, H. A.:  Chorioretinopathy Associated With Other Evidence of Cerebral Damage in Childhood: A Syndrome of Unknown Origin Separable From Congenital Toxoplasmosis , Amer J Dis Child 79:366-368, 1950;.

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