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Hereditary Legg-Calvé-Perthes Disease

Z. WAMOSCHER, MD; A. FARHI, MD
Am J Dis Child. 1963;106(1):97-100. doi:10.1001/archpedi.1963.02080050099016.
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Osteochondritis deformans coxae juvenilis was first described in 1909 by Legg and in 1910 by Calvé and Perthes. Today the disorder is known as Legg-Calvé-Perthes Disease (LCPD). It is one of the commonest disorders of the hip in childhood,1 mainly affecting children between 3-10. The disease is unilateral in 90% of cases, and according to the series of Gill 2 preponderance of 85%-90% in boys is found.

The disease is self-limiting and today it is most commonly accepted that avascular necrosis of the head of the femur is the immediate cause.1,3 Therefore the term "osteochondritis" which implies inflammation is a misnomer.

In the natural history of the disease there are three stages: (1) an early stage of bone necrosis, (2) a stage of regeneration with replacement of the necrotic bone by a viable one, and (3) a healed stage.4 If untreated the disease causes a various amount

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