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Eosinophilic Granuloma of Parotid Gland and Thymus

Am J Dis Child. 1963;105(5):507-510. doi:10.1001/archpedi.1963.02080040509015.
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Introduction  Since the term "eosinophilic granuloma" was coined by Lichtenstein and Jaffé 1 for a recognized bone lesion in 1940, and since the suggested nosologic relationship between Hand-Schüller-Christian, Letterer-Siwe, and eosinophilic granuloma of bone by Farber,2 numerous reports of histologically similar lesions have been reported in the following locations: lung,3 gastrointestinal tract, particularly the stomach,4 skin,5,6 urinary bladder,7 prostate, and vulva.8 It is the intent of this paper to report a case of "eosinophilic granuloma" of the thymus and a case of eosinophilic granuloma occurring in the parotid glands, bilaterally; these both occurred in children.

Report of Cases  Case 1.—This 12-year-old Chinese male was well until three days before admission when he developed fever of 101 F in the evening. During this time he complained of headache, anorexia, epistaxis, and arthralgia of the right knee and left ankle. He was admitted to the hospital with


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