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April 1963, Vol 105, No. 4 >
Article | April 1963

Parathyroid Hyperplasia in an Infant FREE

CLARE RANDALL, M.R.C.S., L.R.C.P.; STUART C. LAUCHLAN, M.B., Ch.B.
[+] Author Affiliations

Submitted for publication Jan. 20, 1962.

A polyvitamin supplement (Horner) containing 0.00014 vitamin D in 5 cc.


Am J Dis Child. 1963;105(4):364-367. doi:10.1001/archpedi.1963.02080040366007.
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Diffuse hyperplasia of the parathyroid glands is a rare condition in infancy, and both the clinical picture and the histologic structure of the parathyroid glands differ somewhat from those of the comparable disorder in adults. As far as we can ascertain, two previous fatal cases1,2 have been reported with both clinical and postmortem descriptions. In addition, a probable further example of this condition, with apparently successful surgical intervention, has been reported by Landon.3 In these three cases the disease process was present in early infancy, and in two of the cases it proved fatal. The present report describes a further example of infantile hyperparathyroidism resulting from diffuse hyperplasia of the parathyroid glands.

Report of Case  The patient was born in May, 1960, the first child of a deaf and dumb, severely mentally retarded mother. At birth he weighed 5 lb. 4¼ oz. (about 2,388 gm.). He was admitted

REFERENCES

1 +
Pratt, E. L.; Geren, B. B., and Neuhauser, E. B. D.:  Hypercalcaemia and Idiopathic Hyperplasia of the Parathyroid Glands in an Infant , J. Pediat. 30:388, 1947;.
2 +
Philips, R. N.:  Primary Diffuse Parathyroid Hyperplasia in an Infant of 4 Months , Pediatrics 2:428, 1948;.
3 +
Landon, J. F.:  Parathyroidectomy in Generalized Osteitis Fibrosa Cystica , J. Pediat. 1:544, 1932;.
4 +
Kaplan, E.:  The Parathyroid Gland in Infancy , Arch. Path. 34:1042, 1942;.
5 +
Cope, O.; Keynes, W. M.; Roth, S. I., and Castleman, B.:  Primary Chief-Cell Hyperplasia of the Parathyroid Glands , Ann. Surg. 148:375, 1958;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Pratt, E. L.; Geren, B. B., and Neuhauser, E. B. D.:  Hypercalcaemia and Idiopathic Hyperplasia of the Parathyroid Glands in an Infant , J. Pediat. 30:388, 1947;.
2 +
Philips, R. N.:  Primary Diffuse Parathyroid Hyperplasia in an Infant of 4 Months , Pediatrics 2:428, 1948;.
3 +
Landon, J. F.:  Parathyroidectomy in Generalized Osteitis Fibrosa Cystica , J. Pediat. 1:544, 1932;.
4 +
Kaplan, E.:  The Parathyroid Gland in Infancy , Arch. Path. 34:1042, 1942;.
5 +
Cope, O.; Keynes, W. M.; Roth, S. I., and Castleman, B.:  Primary Chief-Cell Hyperplasia of the Parathyroid Glands , Ann. Surg. 148:375, 1958;.

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