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Encephalitis Due to Group B, Type 5 Coxsackie Virus

Am J Dis Child. 1963;105(2):209-212. doi:10.1001/archpedi.1963.02080040211014.
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Convincing evidence has been presented of the etiologic association of Group B Coxsackie virus with respiratory tract inflammation, pleurodynia, pericarditis, myositis including myocarditis, and the aseptic meningitis syndrome. Since first noted by Steigman,1 a small but significant percentage of mild, transient, paralytic lower motor-neurone disease clinically indistinguishable from poliomyelitis has been demonstrated to be consequent to Coxsackie Group A and B and ECHO virus infection.2-5 Overt encephalitis with serious neurologic derangement due to Coxsackie virus infection has been, with rare exceptions, confined to infancy and associated with diffuse visceral disease involving the liver and myocardium.6,7 Thus, the occu[ill] rence in a 9-year-old boy of severe encephalitis proved to be associated with Group B, Type 5 Coxsackie virus infection emphasizes the need to reconsider the neurotropic potentialities of this group of agents.

Report of a Case  A 9-year-old Caucasian boy entered the hospital because of persistent vomiting and


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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