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Idiopathic Hypoparathyroidism in Neonatal Period

FRED G. SMITH JR., M.D.; KENNETH ZIKE, M.D.
Am J Dis Child. 1963;105(2):182-187. doi:10.1001/archpedi.1963.02080040184009.
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Idiopathic hypoparathyroidism is rarely diagnosed in the neonatal period. In a recent review Bronsky et al.1 reported 50 cases of idiopathic hypoparathyroidism! Of these, 58% had their onset before 10 years of age; however, only 1 case was diagnosed in the neonatal period. A search of the medical literature has uncovered a total of 7 cases reported in infants under 2 months of age.

In the neonatal period the usual manifestations of idiopathic hypoparathyroidism are major motor seizures, generalized twitching, and hypertonicity. These findings are nonspecific and more commonly suggest disease entities other than idiopathic hypoparathyroidism.

It is the purpose of this paper to report a case of idiopathic hypoparathyroidism diagnosed at 31/2 weeks of age and to reemphasize the importance of considering this diagnosis when the problem of seizures arises in the neonatal period.

Report of Case  A 2½-week-old Mexican male infant was born on Jan. 27, 1960,

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