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October 1962, Vol 104, No. 4 >
Article | October 1962

Simplified Intravascular Hydrogen Electrode Method FREE

MUFIT M. ARCASOY, M.D.; WARREN G. GUNTHEROTH, M.D.; GAY L. MULLINS, B.S.
[+] Author Affiliations

Submitted for publication Dec. 4, 1961.

This work was supported in part by U.S. Public Health Service Grant H-3998.

This paper was presented in part before the Washington State Medical Association, Sept. 28, 1960.


Am J Dis Child. 1962;104(4):349-354. doi:10.1001/archpedi.1962.02080030351005.
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The detection and location of left-to-right shunts is essential in the diagnosis of congenital heart disease. The earliest method for this purpose was analysis of oxygen content or saturation of multiple blood samples from various chambers of the heart and great vessels. This method remains the most widely used, having the advantage of quantitation. However, the amount of blood which is required for this is sometimes dangerously large in infants, and the delay before the results are known may be several hours. In addition, gasometric methods cannot easily be applied in the operating room. The dye-dilution method is excellent for locating right-to-left shunts, but the curves are of no assistance in locating a left-to-right shunt, except using double lumen or double catheter techniques, which are cumbersome and impractical for small children. The method is again limited because of the considerable amount of blood lost, and the accumulation of dye interferes

REFERENCES

1 +
Clark, L. C., Jr., and Misrahy, G. A.: An Electrochemical Method to Measure Hydrogen Gas in Biological Tissue , Abstract 177, XXth International Physiological Congress, Brussels, 1956;.
2 +
Misrahy, G. A., and Clark, L. C., Jr.: Use of the Platinum Black Cathode for Local Blood Flow Measurements in Vivo , Abstract 650, XXth International Physiological Congress, Brussels, 1956;.
3 +
Clark, L. C., Jr., and Bargeron, L. M., Jr.:  Left-to-Right Shunt Detection by an Intravascular Electrode with Hydrogen as an Indicator , Science 130:709-710, 1959;.
4 +
Clark, L. C., Jr., and Bargeron, L. M., Jr.:  Detection and Direct Recording of Left-to-Right Shunts with the Hydrogen Electrode Catheter , Surgery 46:797-804, 1959;.
5 +
Bargeron, L. M., Jr.; Clark, L. C., Jr., and McArthur, K. T.:  The Detection of Intracardiac Shunts in Infants by Use of Intravascular Potentiometric Electrodes , Amer. J. Dis. Child. 100:502-503, 1960;.
6 +
Clark, L. C., Jr.; Bargeron, L. M., Jr.; Lyons, C.; Bradley, M. N., and McArthur, K. T.:  Detection of Right-to-Left Shunts with an Arterial Potentiometric Electrode , Circulation 22:949-955, 1960;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Clark, L. C., Jr., and Misrahy, G. A.: An Electrochemical Method to Measure Hydrogen Gas in Biological Tissue , Abstract 177, XXth International Physiological Congress, Brussels, 1956;.
2 +
Misrahy, G. A., and Clark, L. C., Jr.: Use of the Platinum Black Cathode for Local Blood Flow Measurements in Vivo , Abstract 650, XXth International Physiological Congress, Brussels, 1956;.
3 +
Clark, L. C., Jr., and Bargeron, L. M., Jr.:  Left-to-Right Shunt Detection by an Intravascular Electrode with Hydrogen as an Indicator , Science 130:709-710, 1959;.
4 +
Clark, L. C., Jr., and Bargeron, L. M., Jr.:  Detection and Direct Recording of Left-to-Right Shunts with the Hydrogen Electrode Catheter , Surgery 46:797-804, 1959;.
5 +
Bargeron, L. M., Jr.; Clark, L. C., Jr., and McArthur, K. T.:  The Detection of Intracardiac Shunts in Infants by Use of Intravascular Potentiometric Electrodes , Amer. J. Dis. Child. 100:502-503, 1960;.
6 +
Clark, L. C., Jr.; Bargeron, L. M., Jr.; Lyons, C.; Bradley, M. N., and McArthur, K. T.:  Detection of Right-to-Left Shunts with an Arterial Potentiometric Electrode , Circulation 22:949-955, 1960;.

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