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Measles Serologic Standards FREE

HARRY M. MEYER, M.D.; BARBARA E. BROOKS, M.S.; ROBERT D. DOUGLAS; NANCY G. ROGERS, B.A.
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Presented at the International Conference on Measles Immunization, National Institutes of Health, Bethesda, Md., Nov. 7-9, 1961.


Am J Dis Child. 1962;103(3):495-502. doi:10.1001/archpedi.1962.02080020507071.
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Serologic tests for mealses antibodies became feasible in 1954 when Enders and Peebles 1 demonstrated that the virus could be cultivated in monolayers of human kidney cells. These workers promptly applied 2 of the classical procedures of viral immunology, i.e., the complement fixation (CF) and virus neutralization tests. Others 2-4 subsequently contributed to the growing battery of information obtained with these tools. Recently, Periés and Chany 5 observed that erythrocytes from certain primates were agglutinated by fluids containing measles virus. Several groups6-8 have since described hemagglutination and hemagglutination inhibition employing red corpuscles from a number of common monkey species, thus introducing to measles research still another time-tested instrument of the virologist. As is often the case, each investigator has fashioned these serologic procedures to meet the requirements of his particular study with resultant lack of uniformity in methodology.

This paper is concerned with a study of several variables in

REFERENCES

Enders, J. F., and Peebles, T. C.:  Propagation in Tissue Cultures of Cytopathogenic Agents from Patients with Measles , Proc. Soc. Exp. Biol. Med. 86:277 ( (June) ) 1954;.
Ruckle, G., and Rogers, K. D.:  Studies with Measles Virus: II. Isolation of Virus and Immunologic Studies in Persons Who Have Had the Natural Disease , J. Immun. 78:341 ( (May) ) 1957;.
Black, F. L.:  Measles Antibodies in the Population of New Haven, Connecticut , J. Immun. 83:74 ( (July) ) 1959;.
Bech, V.:  Studies on the Development of Complement Fixing Antibodies in Measles Patients: Observations During a Measles Epidemic in Greenland , J. Immun. 83:267 ( (Sept.) ) 1959;.
Periés, J. R., and Chany, C.:  Activité hémagglutinante et hémolytique du virus morbilleux , C.R. Acad. Sci. (Par.) 251:820 ( (Aug. 1) ) 1960;.
Rosen, L.:  Hemagglutination and Hemagglutination-Inhibition with Measles Virus , Virology 13:139 ( (Jan.) ) 1961;.
De Meio, J. L., and Gower, T. A.:  Hemagglutination by Measles Virus , Virology 13:367 ( (March) ) 1961;.
Rosanoff, E. I.:  Hemagglutination and Hemadsorption of Measles Virus , Proc. Soc. Exp. Biol. Med. 106:563 ( (March) ) 1961;.
Eagle, H.:  Propagation in a Fluid Medium of a Human Epidermoid Carcinoma, Strain KB , Proc. Soc. Exp. Biol. Med. 89:362 ( (July) ) 1955;.
Fogh, J., and Lund, R. O.:  Continuous Cultivation of Epithelial Cell Strain (FL) from Human Amniotic Membrane , Proc. Soc. Exp. Biol. Med. 94:532 ( (March) ) 1957;.
Salk, J. E., and Ward, E. N.:  Some Characteristics of a Continuously Propagating Cell Derived from Monkey Heart Tissue , Science 126:1338 ( (Dec. 27) ) 1957;.
Lennette, E. H.:  General Principles Underlying Laboratory Diagnosis of Virus and Rickettsial Infections , in Diagnostic Procedures for Virus and Rickettsial Diseases , Ed. 2, New York, American Public Health Association, 1956;, pp. 46-49.
Meyer, H. M., Jr.; Brooks, B. E.; Douglas, R. D., and Rogers, N. G.:  Potency Testing of Live Measles Vaccine , Amer. J. Dis. Child. 103: this issue, page 457.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Enders, J. F., and Peebles, T. C.:  Propagation in Tissue Cultures of Cytopathogenic Agents from Patients with Measles , Proc. Soc. Exp. Biol. Med. 86:277 ( (June) ) 1954;.
Ruckle, G., and Rogers, K. D.:  Studies with Measles Virus: II. Isolation of Virus and Immunologic Studies in Persons Who Have Had the Natural Disease , J. Immun. 78:341 ( (May) ) 1957;.
Black, F. L.:  Measles Antibodies in the Population of New Haven, Connecticut , J. Immun. 83:74 ( (July) ) 1959;.
Bech, V.:  Studies on the Development of Complement Fixing Antibodies in Measles Patients: Observations During a Measles Epidemic in Greenland , J. Immun. 83:267 ( (Sept.) ) 1959;.
Periés, J. R., and Chany, C.:  Activité hémagglutinante et hémolytique du virus morbilleux , C.R. Acad. Sci. (Par.) 251:820 ( (Aug. 1) ) 1960;.
Rosen, L.:  Hemagglutination and Hemagglutination-Inhibition with Measles Virus , Virology 13:139 ( (Jan.) ) 1961;.
De Meio, J. L., and Gower, T. A.:  Hemagglutination by Measles Virus , Virology 13:367 ( (March) ) 1961;.
Rosanoff, E. I.:  Hemagglutination and Hemadsorption of Measles Virus , Proc. Soc. Exp. Biol. Med. 106:563 ( (March) ) 1961;.
Eagle, H.:  Propagation in a Fluid Medium of a Human Epidermoid Carcinoma, Strain KB , Proc. Soc. Exp. Biol. Med. 89:362 ( (July) ) 1955;.
Fogh, J., and Lund, R. O.:  Continuous Cultivation of Epithelial Cell Strain (FL) from Human Amniotic Membrane , Proc. Soc. Exp. Biol. Med. 94:532 ( (March) ) 1957;.
Salk, J. E., and Ward, E. N.:  Some Characteristics of a Continuously Propagating Cell Derived from Monkey Heart Tissue , Science 126:1338 ( (Dec. 27) ) 1957;.
Lennette, E. H.:  General Principles Underlying Laboratory Diagnosis of Virus and Rickettsial Infections , in Diagnostic Procedures for Virus and Rickettsial Diseases , Ed. 2, New York, American Public Health Association, 1956;, pp. 46-49.
Meyer, H. M., Jr.; Brooks, B. E.; Douglas, R. D., and Rogers, N. G.:  Potency Testing of Live Measles Vaccine , Amer. J. Dis. Child. 103: this issue, page 457.

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