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January 1961, Vol 101, No. 1 >
Article | January 1961

Colorado Tick Fever

HENRY K. SILVER, M.D.; GORDON MEIKLEJOHN, M.D.; C. HENRY KEMPE, M.D.
Am J Dis Child. 1961;101(1):30-36. doi:10.1001/archpedi.1961.04020020032006.
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Each year Americans engage in more and more travel, with the result that illnesses that were formerly primarily of interest to only one geographic area of the country now must be recognized by physicians in areas far removed from the site where the disease may have been acquired. The purpose of this paper is to call attention to Colorado tick fever, a relatively common acute infectious disease with a characteristic doublehumped intermittent fever, present throughout much of the western part of the United States, and the only tick-transmitted virus infection of man occurring in the Western hemisphere.

Despite the relative frequency of this disease, it is surprising that it was not recognized as a specific disease entity until well into the 20th century. It would appear to have been a disease of the white man since he first came to the Rocky Mountain region and probably was present among the

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