We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Atropine Response of the Eyes in Mongolism

Am J Dis Child. 1960;100(6):869-872. doi:10.1001/archpedi.1960.04020040871010.
Text Size: A A A
Published online


Introduction  Other investigators1 have reported a more rapid and sustained dilatation of the pupils of Mongols as compared to non-Mongols when atropine was instilled locally into the eyes. These observations were interpreted as indicating a possible hypersensitivity to atropine on the part of Mongols. We also were interested in investigating the response of Mongols to atropine since documentation of a difference in response to this drug would have therapeutic and possibly diagnostic implications. In this institution for the retarded there are over 200 patients with Mongolism. It has not been our experience that these patients show unusual systemic response to atropine although this drug has been used here for some years, particularly as a preanesthetic medication. We have not observed gross EEG changes or changes in sensorium, pulse rate, or respiratory rate with the usual dosage. Lowe2 reported in his extensive study of the eyes of Mongols that


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.