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The Heaf Multiple Puncture Tuberculin Test FREE

SHIRLEY RUTH ANDERSEN, M.D.; MARGARET H. D. SMITH, M.D.
[+] Author Affiliations

Submitted for publication Sept. 25, 1959.

Presented at the Annual Meeting of the American Trudeau Society, Philadelphia, May, 1958.

The standardized PPD-S, 5 TU strength, was kindly furnished by Dr. Lydia Edwards, Division of Tuberculosis, U.S. Public Health Service, Washington, D.C.

The "Heaf guns" were obtained from Allen and Hanbury, Ltd., Bethnal Green, London, E2; from H. G. East & Co., Ltd., Cowley, Oxford, England; as well as from the Panray Corporation, Englewood, N.J., through the kindness of Mr. H. Silver, who also furnished the "Protoderm."


AMA Am J Dis Child. 1960;99(6):764-769. doi:10.1001/archpedi.1960.02070030766011.
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Pediatricians and public health authorities alike have recently displayed renewed interest in tuberculous infections in children. Recent studies both in this country1 and in France2 have shown beyond doubt that administration of antituberculous drugs to children with positive tuberculin tests decreases the chance of active tuberculous disease appearing within the ensuing year, so that it becomes desirable to detect infection with Mycobacterium tuberculosis soon after it has taken place. This can best be done by carrying out tuberculin tests at rather frequent intervals, e.g., once or preferably twice a year. There is now, more than ever before, a clear need for a simple, reliable method for performing tuberculin tests, so that they can be performed repeatedly on large groups of young people. The tuberculin patch test which, it was hoped, would serve such a purpose has proved disappointing, yielding as it does both false positive and false negative

REFERENCES

Ferebee, S.; Mount, F. W., and Anastasiades, A.:  Prophylactic Effects of Isoniazid on Primary Tuberculosis in Children: Preliminary Report , Am. Rev. Tuberc. 76:942, 1957;.
Brissaud, H. E.; Kaplan, A. S.; Noufflard, H.; Raymond, J.; Hanoteau, J., and Pignier, J.:  Traitement de la tuberculose initiale chez l'enfant , Pédiatrie 13:369, 1958;.
Heitz, J. E., and Young, R. C.:  The Inadequacy of the Vollmer Tuberculin Patch Test in Adults , Canad. M.A.J. 76:718, 1957;.
Waegele, V. C., Rothrock, W. J., and Van Scoyoc, R.:  Simultaneous Mantoux and Vollmer Patch Tests in 855 School Children , Dis. Chest 31: 635, 1957;.
Heaf, F.:  The Multiple Puncture Tuberculin Test , Lancet 2:151, 1951;.
Heaf, F.:  The Multiple Puncture Tuberculin Test , Tubercle 34:335, 1953;.
Anderson, A. W.:  Experiences with the Heaf Multiple Puncture Tuberculin Tester , Tubercle 35: 18, 1954;.
Irvine, K. N.:  Observations on the Heaf Multiple Puncture Test , Tubercle 36:21, 1955;.
Stott, H.:  Heaf's Multiple Puncture Test Compared with the Mantoux Test (0.1 mg. O.T.) , Tubercle 36:119, 1955;.
Thompson, B.:  A Tuberculosis Survey in Broadmoor: Experience with the Heaf Multiple-Puncture Tuberculin Test , Tubercle 36:18, 1955;.
Stradling, P.:  Modification of the Heaf Test , Letter to the Editor, Lancet 2:252, 1955;.
Low, E.:  Mantoux and Heaf Multiple Puncture Tuberculin Tests: Comparison in BCG Vaccinated and Unvaccinated Subjects , Tubercle 37: 102, 1956;.
Townsend, R. L.:  The Heaf Multiple Puncture Tuberculin Test in Relation to the Army BCG Scheme , Proc. Roy. Soc. Med. 49:322, 1956;.
De Hamel, F. A.:  A Trial of Heaf and Mantoux Tuberculin Tests , New Zealand M.J. 56:659, 1957;.
Briggs, I. L., and Smith, C.:  BCG Vaccination by the Multiple Puncture Method in Northern Rhodesia , Tubercle 38:107, 1957;.
Henshaw, J. E.:  Comparative Study of Heaf Tuberculin Tests with PPD and Freeze Dried BCG Vaccine , Tubercle 38:411, 1957;.
Stewart, C. J.; Carpenter, R. G., and McCauley, P.:  Reliability of the Multiple Puncture Tuberculin Test Compared with the Mantoux Test , Tubercle 39:143, 1958;.
 A Single Tuberculin Test for Epidemiological Use: Comparison of Four Tests; a Report to the Research Committee of the British Tuberculosis Association , Tubercle 39:76, 1958;.
Heaf, F.:  Multiple Puncture Tuberculin Test , Correspondence, Tubercle 34:335, 1953;.
Heaf, F.: Personal communication to the authors.
Baker, J. M., and Smith, M. H. D., to be published.

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References

Ferebee, S.; Mount, F. W., and Anastasiades, A.:  Prophylactic Effects of Isoniazid on Primary Tuberculosis in Children: Preliminary Report , Am. Rev. Tuberc. 76:942, 1957;.
Brissaud, H. E.; Kaplan, A. S.; Noufflard, H.; Raymond, J.; Hanoteau, J., and Pignier, J.:  Traitement de la tuberculose initiale chez l'enfant , Pédiatrie 13:369, 1958;.
Heitz, J. E., and Young, R. C.:  The Inadequacy of the Vollmer Tuberculin Patch Test in Adults , Canad. M.A.J. 76:718, 1957;.
Waegele, V. C., Rothrock, W. J., and Van Scoyoc, R.:  Simultaneous Mantoux and Vollmer Patch Tests in 855 School Children , Dis. Chest 31: 635, 1957;.
Heaf, F.:  The Multiple Puncture Tuberculin Test , Lancet 2:151, 1951;.
Heaf, F.:  The Multiple Puncture Tuberculin Test , Tubercle 34:335, 1953;.
Anderson, A. W.:  Experiences with the Heaf Multiple Puncture Tuberculin Tester , Tubercle 35: 18, 1954;.
Irvine, K. N.:  Observations on the Heaf Multiple Puncture Test , Tubercle 36:21, 1955;.
Stott, H.:  Heaf's Multiple Puncture Test Compared with the Mantoux Test (0.1 mg. O.T.) , Tubercle 36:119, 1955;.
Thompson, B.:  A Tuberculosis Survey in Broadmoor: Experience with the Heaf Multiple-Puncture Tuberculin Test , Tubercle 36:18, 1955;.
Stradling, P.:  Modification of the Heaf Test , Letter to the Editor, Lancet 2:252, 1955;.
Low, E.:  Mantoux and Heaf Multiple Puncture Tuberculin Tests: Comparison in BCG Vaccinated and Unvaccinated Subjects , Tubercle 37: 102, 1956;.
Townsend, R. L.:  The Heaf Multiple Puncture Tuberculin Test in Relation to the Army BCG Scheme , Proc. Roy. Soc. Med. 49:322, 1956;.
De Hamel, F. A.:  A Trial of Heaf and Mantoux Tuberculin Tests , New Zealand M.J. 56:659, 1957;.
Briggs, I. L., and Smith, C.:  BCG Vaccination by the Multiple Puncture Method in Northern Rhodesia , Tubercle 38:107, 1957;.
Henshaw, J. E.:  Comparative Study of Heaf Tuberculin Tests with PPD and Freeze Dried BCG Vaccine , Tubercle 38:411, 1957;.
Stewart, C. J.; Carpenter, R. G., and McCauley, P.:  Reliability of the Multiple Puncture Tuberculin Test Compared with the Mantoux Test , Tubercle 39:143, 1958;.
 A Single Tuberculin Test for Epidemiological Use: Comparison of Four Tests; a Report to the Research Committee of the British Tuberculosis Association , Tubercle 39:76, 1958;.
Heaf, F.:  Multiple Puncture Tuberculin Test , Correspondence, Tubercle 34:335, 1953;.
Heaf, F.: Personal communication to the authors.
Baker, J. M., and Smith, M. H. D., to be published.

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