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Marfan's Syndrome (Arachnodactyly) with Arthrogryposis (Amyoplasia Congenita)

AMA Am J Dis Child. 1960;99(1):101-106. doi:10.1001/archpedi.1960.02070030103018.
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Since Marfan's syndrome was first reported by Marfan,17 in 1896, several hundred cases of this condition have been recorded in the literature. Although contractures and deformities limited to the hands and feet are not unusual in this disorder and an occasional report has mentioned involvement of either the knees or elbows,11,27 an associated widespread restriction of mobility of a number of joints producing the clinical picture of arthrogryposis is rare in arachnodactyly, and we have been able to find only one such previously reported case.15 The purpose of this paper is to present an infant with the findings of both Marfan's syndrome and arthrogryposis and to review briefly both conditions.

Report of Case  This 6-week-old girl was the first child of a 27-year-old dental technician who had worked in a dental office for one week in the third and fifth month of pregnancy. There was no family


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