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Congenital Cutaneous Candidiasis in a Premature Infant

HARRY SONNENSCHEIN, M.D.; HARRY L. CLARK, M.D.; CLAIRE L. TASCHDJIAN, B.Sc.
AMA Am J Dis Child. 1960;99(1):81-85. doi:10.1001/archpedi.1960.02070030083014.
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Introduction  Neonatal cutaneous candidiasis rarely occurs before the fifth day of life, and is usually associated with oral thrush. The initial lesions are confined to the perianal area and the adjacent glabrous skin. In these cases Candida albicans is always present in the stools, and the skin lesions are presumed to be secondary to an intestinal focus.1,2 More extensive skin involvement, especially of the upper part of the body, is rarely seen before the third or fourth month of life.3,4The case to be described here is unusual because a premature infant was born with extensive candidal lesions involving the glabrous skin of almost the entire body, including the intertriginous and flexor areas of the extremities. The infection must have been contracted in utero. To our knowledge, no similar case has been reported previously.

Report of Case  The mother of the infant was a 24-year-old woman. Her last

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